Study of the Effects of Chemotherapy on Memory and Other Mental Functions in Women With Breast Cancer

Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog. The current study is investigating this phenomenon by measuring mental function of breast cancer patients prior to and after exposure to chemotherapy, and by comparing mental function in those patients who receive chemotherapy and those who do not.

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Key information

Conditions

Breast Cancer Breast Diseases Breast Neoplasms Chemically-Induced Disorders Chemotherapy-Related Cognitive Impairment Cognition Disorders Cognitive Dysfunction Drug-Related Side Effects and Adverse Reactions Mental Disorders Neoplasms Neoplasms by Site Neurocognitive Disorders Skin Diseases Skin and Connective Tissue Diseases

Age range

50 year–65 year

Sex eligibility

Female

Study type

Observational

About this study

Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog. The current study will investigate this phenomenon by measuring neuropsychological functioning in early stage breast cancer patients prior to and after exposure to chemotherapy, and by comparing change in cognitive function in patients who receive chemotherapy to similar breast cancer patients receiving hormonal therapy only.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

stage I or II breast cancer; woman; 50-65 years old; post-menopausal

Exclusion criteria

history of previous cancer or chemotherapy; significant neurological or psychiatric history

Sponsors and collaborators

Lead sponsor

Ottawa Hospital Research Institute

Other

Collaborators

Canadian Breast Cancer Foundation

Registry information

Official study title

A Prospective, Longitudinal Investigation of the Neuropsychological and Psychosocial Effects of Cancer Therapy

Important dates

Study start: 2001
Primary completion: 2008
Study completion: 2008
First posted: Dec 2, 2005
Registry last updated: Sep 25, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed