Chu Dijon Bourgogne
Dijon, 21000, France
Location status: Recruiting
Recruiting
NCT Number: NCT06282601
STUDY OF THE EFFECT OF RHYTHMIC AND NON-RHYTHMIC MUSICAL PRIMING ON THE SYNTAX CAPACITY OF PRESBYACOUSTIC OLDER ADULTS
Presbyacusis, or age-related hearing loss, is a public health problem, affecting 20% of men and 30% of women over the age of 70 according to the WHO. In the most incapacitating cases, hearing aids are required. Numerous studies have evaluated the benefits of hearing aids, particularly in terms of improved hearing and quality of life.
However, the specific effect of music on language skills has not yet been studied in hearing-impaired older adults.
In this context, it was decided to study the effect of musical priming on the syntactic abilities of adults aged 70 or older with presbyacusis.
This study is based on the hypothesis that music priming with regular music optimizes the syntax language skills of people with presbyacusis, as has already been proven in adults and normal-hearing children.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
70 year and older
Sex eligibility
All sexes
Study type
Interventional
Phase
Not applicable
Primary location
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- No objection to participation in the study
- Men and women aged ≥ 70 years
- Patients diagnosed with presbyacusis (age-related bilateral and symmetrical sensorineural hearing loss, all stages combined), with or without the use of a bilateral hearing aid.
- If they use a hearing aid: hearing must have an average free-field fitted tonal threshold of 40 dB max and free-field fitted speech discrimination without lip-reading of 90-100% at 60dB in silence.
- MMSE score ≥ 24/30
Exclusion criteria
- Person under legal protection (curatorship, guardianship)
- Person under court order
- Adult unable to provide consent
- Person with a neurocognitive disorder (post-stroke, dyslexia, dyspraxia) or neuro-psychiatric disorder (dementia, autism)
- Severe sensorineural hearing loss with mean free-field threshold > 40 dB and free-field speech discrimination without lip-reading of < 90-100% at 60dB in silence
- Asymmetrical sensorineural hearing loss due to an additional cause of hearing loss on one side.
Secondary exclusion criteria:
Person with syntax disorder (discovery of sentence comprehension or production disorders during syntax test)
Treatment and study plan
Audiogram
OtherTonal and vocal free-field without lip-reading
Musical priming for the syntax test
OtherListening to music with a regular or irregular rhythm, then judging the grammaticality of 2x6 blocks of French sentences interrupted by a pause, each block presenting 4 sentences including 2 grammatically correct sentences and 2 grammatically incorrect sentences. The sentences are pronounced by a French female voice at a natural rhythm and comfortable volume.
Test MMSE
Othertest to assess a person's cognitive functions and memory capacity.
Barcelona Music Reward Questionnaire
Other20 questions exploring 5 main facets of the musical reward experience, with 4 items for each of the 5 facets, for which participants indicate the level of agreement using a 5-level scale, ranging from "strongly disagree" to "strongly agree".
Primary outcomes
-
linguistic performance test focusing on syntax.
Time frame: At baseline
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Centre Hospitalier Universitaire Dijon
Other
Registry information
Acronym: AMORCAGE MUSIC
Important dates
- Study start
- 2025
- Primary completion
- 2027
- Study completion
- 2027
- First posted
- Feb 28, 2024
- Registry last updated
- Jun 11, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.