Study of Soft Contact Lens Use With 7 Day Extended Wear

To compare the safety and efficacy of the CVI silicone-hydrogel lens worn on an extended wear basis for a period of up to 7 days and 6 nights with the Acuvue 2 soft contact lenses in this open-labeled randomized study.

Inclusion criteria

• Be at least 18 years of age as of the date of evaluation.
• Require lens powers between -0.50 and -6.00 diopters sphere with no more than 1.00 diopter of refractive astigmatism and be willing to wear lenses in both eyes.
• Be correctable to visual acuities of at least 20/25 in each eye with spectacles.
• Be in good general health, based on his/her knowledge.
• Be able and willing to adhere to the instructions set forth in this protocol and able to keep all specified appointments.
• Possess wearable and visually functional eyeglasses.

Exclusion criteria

• Previously unsuccessful with contact lens wear.
• Rigid gas permeable contact lens wear within the past 12 months.
• Previous refractive surgery; current or previous orthokeratology treatment.
• Subject is wearing lenses in a modified monovision modality (multifocal lens in one eye). NOTE: subjects may not wear monovision lenses at any time during the study unless they are wearing spherical monovision lenses prior to enrollment.
• Aphakia, keratoconus or an irregular cornea.
• A known history of corneal hypoesthesia
• Clinically significant (grade 3 or 4) anterior segment abnormalities or any infection of the eye, lids, or associated structures.
• Ocular or systemic disease or need for medication which might interfere with contact lens wear. i.e., Sjögren's syndrome, type II diabetes, etc.
• Slit lamp findings that would contraindicate contact lens wear, including but not limited to:

• History of corneal ulcer, corneal infiltrates or fungal infections.
• Pterygium, pinguecula or corneal scars within the visual axis
• Pathological dry eye or associated findings (examples: Sjögren's syndrome, lupus erythematosus, sclerodermia)
• Neovascularization or ghost vessels > 1mm in from the limbus
• Seborrheic eczema, seborrheic conjunctivitis
• History of papillary conjunctivitis greater than Grade 2 (Mild)
• Anterior uveitis or iritis (past or present)
• Known sensitivity to the care systems used in this study.
• Poor personal hygiene
• Current pregnancy or is lactating (to the best of the subject's knowledge) or subject is planning pregnancy within the next 13 months.
• Any active participation in another clinical study within 30 days prior to this study.
• Subject is a member, relative or household member of the office staff, including the investigator(s).

Subjects must read, indicate understanding of, and sign the Informed Consent Form.