Study of Pasireotide Long Acting Release (LAR) Injection in Patients With Acromegaly and Patients With Carcinoid Disease

Inclusion criteria

for patients with acromegaly:

• Male or female patients between 18 and 80 years
• Patients with acromegaly due to a pituitary adenoma with elevated GH and IGF-1 concentrations

Exclusion criteria

for patients with acromegaly:

• Patients with compression of the optic chiasm causing any visual field defect
• Specific criteria apply for patients who have received certain types of therapies such as radiotherapies, surgeries, chemo- or immunotherapies in the months prior to study start
• Female patients who are pregnant or lactating

Inclusion criteria

for patients with carcinoid disease:

• Male or female patients aged ≥18 years
• Patients with histologically confirmed, metastatic carcinoid tumors of the digestive system
• Patients with elevation of chromogranin-A (CgA) and/or serotonin
• Patients who are not adequately controlled by somatostatin analogues

Exclusion criteria

for patients with carcinoid disease:

• Specific criteria apply for patients who have received certain types of therapies such as radiotherapies, surgeries, chemo- or immunotherapies in the months prior to study start
• Female patients who are pregnant or lactating

Other protocol-defined in- and exclusion criteria may apply.