Skip to main content
OpenTrials
Completed

NCT Number: NCT00322283

Study of Oglemilast for the Prevention of Asthma.

The purpose of this study is to determine whether it is effective in the treatment of exercise-induced asthma and investigate the safety of oglemilast.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Exercise-induced Asthma Asthma Asthma, Exercise-Induced Behavior Bronchial Diseases Exercise-Induced Allergies Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Motor Activity Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Forest Investigative Site, Los Angeles, California, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • stable mild asthma patients who exhibit at least a 20% decrease in FEV1 following exercise.

Exclusion criteria

  • pulmonary disease other than asthma, psychiatric illness, active cardiac disease, high blood pressure, history of substance abuse, current smokers.

Treatment and study plan

Oglemilast

Drug

Oglemilast, 15mg once per day, oral administration

Placebo

Drug

Dose-marched placebo, once per day, oral administration

Primary outcomes

  1. To determine the efficacy of oglemilast as compared to placebo in preventing exercise-induced asthma following 15 days of treatment.

Secondary outcomes

  1. To evaluate the safety of oglemilast over 2 weeks as determined by adverse events, physical examinations, vital signs, electrocardiograms, and laboratory examinations.

Sponsors and collaborators

Lead sponsor

Forest Laboratories

Industry

Registry information

Official study title

Efficacy and Safety of Oglemilast in the Prevention of Exercise-Induced Bronchospasm

Important dates

Study start
2006
Primary completion
2006
Study completion
2006
First posted
May 5, 2006
Registry last updated
Apr 10, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.