Study of Iron Accumulation Measured in MRI in Non-pathological Aging

To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

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Key information

Conditions

Healthy Aging

Age range

18 year–95 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hopital Roger Salengro, CHU Lille

Lille, 59037, France

Location status: Recruiting

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Men or women between 18 and 95 years old
French speaker with capability to understand the instructions
Health insurance

Exclusion criteria

Pregnancy
minor subject
no informed consent agreement
subject enrolled in pharmaceutic study or exclusion period
MRI contra-indications
Neurological or psychiatric disorders
MOCA < 26
Psychotropic drugs
More than 3 MRI exams
More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months
Unable to follow the entire protocol according to the investigator

Treatment and study plan

Primary outcomes

Correlation coefficient between iron load in MRI and age

Time frame: baseline

Study contacts

Contact information is provided by the study sponsor or research team.

Grégory KUCHCINSKI, MD

CONTACT

[email protected]

0320445962 ext. +33

Sponsors and collaborators

Lead sponsor

University Hospital, Lille

Other

Registry information

Acronym: FER-IRM

Important dates

Study start: 2023
Primary completion: 2029
Study completion: 2029
First posted: Dec 9, 2020
Registry last updated: May 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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