Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS)

Study of immunosuppression biomarkers in patients with ARDS or cardiogenic shock with ECMO / ECLS, compared to patients with ARDS or cardiogenic shock without ECMO / ECLS

Completed

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Key information

Conditions

Acute Respiratory Distress Syndrome Cardiogenic Shock Cardiovascular Diseases Heart Diseases Infarction Ischemia Lung Diseases Myocardial Infarction Myocardial Ischemia Necrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Distress Syndrome Respiratory Tract Diseases Shock Shock, Cardiogenic Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU de Rennes

Rennes, 35033, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient older than 18 years old
Patient hospitalized in an intensive care unit
Patient whose initial ARDS or Cardiogenic shock began less than 5 days before admission
Patients hospitalized for ARDS or Cardiogenic shock with ECMO / ECLS or - Patients hospitalized for ARDS or Cardiogenic shock without ECMO / ECLS

Exclusion criteria

Opposition of patient, relative or legal representative for participation in the study
Pregnant woman
Pre-immunodepression
Implementation of immunosuppressive therapy such as chemotherapy, cyclophosphamide, high-dose corticosteroids (> 0.5mg / kg / day).

Treatment and study plan

blood test

Biological

Primary outcomes

Prevalence of immunosuppression in patients with ARDS or cardiogenic shock under ECMO / ECLS hospitalized in intensive care unit

Time frame: Hour 24

Sponsors and collaborators

Lead sponsor

Rennes University Hospital

Other

Registry information

Acronym: IMPEC

Important dates

Study start: 2017
Primary completion: 2019
Study completion: 2019
First posted: Aug 25, 2017
Registry last updated: Apr 12, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed