Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans

Determine if:

* genetic differences of CNDP1 gene * the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents * psychometric * other variables can differentiate between veterans of the 1990-1991 Persian Gulf War who have autonomic, neurological and other symptoms and those without these complaints.

Completed

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Key information

Conditions

Gulf War Illness Behavior Brain Diseases Central Nervous System Diseases Colonic Diseases Colonic Diseases, Functional Digestive System Diseases Disorders of Environmental Origin Environmental Illness Fibromyalgia Gastrointestinal Diseases Headache Disorders Headache Disorders, Primary Hypersensitivity Immune System Diseases Intestinal Diseases Irritable Bowel Syndrome Migraine Disorders Motor Activity Multiple Chemical Sensitivity Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neuromuscular Diseases Occupational Diseases Persian Gulf Syndrome Persian Gulf War Syndrome Rheumatic Diseases War-Related Injuries Wounds and Injuries

Sex eligibility

All sexes

Study type

Observational

Primary location

Georgetown University

Washington D.C., District of Columbia, 20007, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Evidence of military enlistment between August 1, 1990 and July 31, 1991, and deployment for 30 consecutive days to:

Persian Gulf waters and adjacent land areas
Other global locations
U.S. only
Status prior to 1990 and 1991:

Active duty
National Guard
Reserves

Exclusion criteria

Current active duty military personnel
Any one who was not active duty military personnel between August 1, 1990 and July 31, 1991
HIV/AIDS; pregnancy or lactation; potential hepatitis; drug addiction; chronic inflammatory, infectious, or autoimmune medical illnesses not associated with GWI; incarceration; dementia, other cognitive limitation; or reliance on a care-giver in order to respond to the questionnaires and other study tests.

Amputations of one or both hands and forearms will be permitted but hand grip tests will not be tested

Sponsors and collaborators

Lead sponsor

Georgetown University

Other

Collaborators

U.S. Army Medical Research and Development Command

Registry information

Official study title

CNDP1 Polymorphisms in Gulf War Illness (GWI)

Important dates

Study start: 2008
Primary completion: 2011
Study completion: 2011
First posted: Dec 18, 2008
Registry last updated: Jun 18, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed