Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women.

The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count.

The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.

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Key information

Conditions

Antral Follicle Deficit Fertility

Age range

18 year–35 year

Sex eligibility

Female

Study type

Observational

Primary location

Antoine Beclere Hospital, Obstetrics and Gynaecology and Reproduction Medicine Service

Paris, 92140, France

About this study

The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

18 to 35 years old
1 to 9 or 13 to 20 antral follicles
Caucasian, occidental Europe
Presence of both ovaries
Informed consent

Exclusion criteria

Ovarian anomalies
Menopause
Pregnancy
Other diseases

Treatment and study plan

Blood samples

Procedure

Blood samples

Sponsors and collaborators

Lead sponsor

Assistance Publique - Hôpitaux de Paris

Other

Registry information

Important dates

Study start: 2005
Primary completion: 2009
Study completion: 2009
First posted: Oct 4, 2005
Registry last updated: Jan 6, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed