Clinical Trial Site
Auckland, New Zealand
NCT Number: NCT04940559
This was a randomized, crossover, open-label study to assess the relative bioavailability, pharmacokinetics (PK), and safety of three different formulations of danicopan (tablet, softgel capsule, liquid-filled capsule [LFC]) in healthy participants.
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Notify Me18 year–55 year
All sexes
Interventional
Phase 1
Auckland, New Zealand
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Key Inclusion Criteria:
Key Exclusion Criteria:
Oral tablet.
Other names: ALXN2040, ACH-0144471 (formerly), ACH-4471, ACH4471, 4471
Oral softgel capsule.
Other names: ALXN2040, ACH-0144471 (formerly), ACH-4471, ACH4471, 4471
Oral LFC.
Other names: ALXN2040, ACH-0144471 (formerly), ACH-4471, ACH4471, 4471
Time frame: Up to 96 hours postdose
Time frame: Up to 96 hours postdose
Time frame: Up to 96 hours postdose
Time frame: Up to 96 hours postdose
Time frame: Up to 96 hours postdose
Time frame: Up to 96 hours postdose
Time frame: Day 1 through Day 39
Alexion Pharmaceuticals, Inc.
Industry
A Phase 1 Study To Determine The Relative Bioavailability Of ACH-0144471 After Administration Of A Tablet Or Softgel Capsule Versus A Liquid Filled Capsule In Healthy Volunteers
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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