Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives

RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.

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Key information

Conditions

Sarcoma Neoplasms Neoplasms by Histologic Type Neoplasms, Bone Tissue Neoplasms, Connective Tissue Neoplasms, Connective and Soft Tissue Neoplasms, Germ Cell and Embryonal Neoplasms, Glandular and Epithelial Neoplasms, Nerve Tissue Neoplasms, Neuroepithelial Neuroectodermal Tumors Neuroectodermal Tumors, Primitive Neuroectodermal Tumors, Primitive, Peripheral Osteosarcoma Sarcoma, Ewing

Age range

0 year–120 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Institut Curie Hopital

Paris, 75005, France

About this study

OBJECTIVES:

To identify and characterize a genetic susceptibility factor to Ewing's sarcoma by performing a Genome-Wide Association Study with as many as possible Ewing sarcoma patients.

OUTLINE: This is a multicenter study.

Blood samples are collected from patients and their relatives. Blood DNA samples are analyzed for susceptibility genes of Ewing Sarcoma.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

DISEASE CHARACTERISTICS:

Patients with Ewing sarcoma
Relatives of Ewing sarcoma patients

PATIENT CHARACTERISTICS:

Patients with a fusion genes specific of Ewing Sarcoma

PRIOR CONCURRENT THERAPY:

Not applicable

Treatment and study plan

genome-wide association study

Other

Primary outcomes

Identification and characterization of susceptibility genes in patients with Ewing sarcoma

Time frame: Through study completion, an average of 10 years

Identification and characterization of susceptibility genes in patients with Ewing sarcoma

Sponsors and collaborators

Lead sponsor

Institut Curie

Other

Registry information

Official study title

GENEWING - A Genome Wide Association Study in Ewing Sarcoma

Acronym: GENEWING

Important dates

Study start: 2010
Primary completion: 2019
Study completion: 2019
First posted: Sep 28, 2010
Registry last updated: May 19, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed