Skip to main content
OpenTrials
Completed

NCT Number: NCT00549393

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

The investigators propose to conduct a large clinical study to determine if daily bathing with chlorhexidine impregnated cloths will reduce the incidence of healthcare-associated infections in the Pediatric Intensive Care Unit (PICU).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Nosocomial Infections Cross Infection Disease Attributes Iatrogenic Disease Infections Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

2 month–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Children's National Medical Center, Washington D.C., District of Columbia, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients in pediatric intensive care unit

Exclusion criteria

  • Patients with a history of an allergic reaction to chlorhexidine
  • Patients less than 2 months of age
  • Patients with severe skin disease or burn
  • Patients with an indwelling epidural catheter or lumbar drain

Treatment and study plan

2% Chlorhexidine gluconate cloth

Drug

Daily bathing

Primary outcomes

  1. Bacteremia

    Time frame: participants were followed for the duration of ICU stay, median stay 3 days

    incidence of bacteremia comparing those in treatment and control groups

Secondary outcomes

  1. Central Line Associated-bloodstream Infection (CLABSI)

    Time frame: participants were followed for the duration of ICU stay, median stay 3 days

    Comparing incidence of central line-associated bloodstream infections between treatment and control groups

Other outcomes

  1. Bacteremia

    Time frame: duration of ICU stay, median 3 days

    per protocol analysis of incidence of bacteremia comparing those in treatment and control groups

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Collaborators

  • Sage Products, Inc.

Registry information

Official study title

Impact of Daily Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

Important dates

Study start
2008
Primary completion
2010
Study completion
2012
First posted
Oct 25, 2007
Registry last updated
Jun 14, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.