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OpenTrials
Completed

NCT Number: NCT01805349

Study of Association Between Digital Osteoarthritis and Lower Limb Osteoarthritis

Among the risk factors for lower limb osteoarthritis, if obesity is probably the most studied, digital osteoarthritis received increasing interest in recent years. Recent publications have highlighted a link between obesity and digital osteoarthritis, but also a very probable link between digital osteoarthritis and structural progression of knee osteoarthritis. Few data including hip exist and need to be confirmed on larger scale studies. We have with "Khoala" a national multiregional cohort of symptomatic gonarthrosis and coxarthrosis representative of the general population (which is rarely the case in the literature) including X ray, clinical and biological follow-up (hips and / or knees).

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Key information

Conditions

Digital Arthrosis

Age range

40 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of rheumatology, nice university hospital

Nice, 06000, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • men or women aged 40 to 75 years
  • with symptomatic osteoarthritis of the hip and / or knee (femoro-tibial), unilateral or bilateral
  • with a confirmed diagnosis (criteria of the American College of Rheumatology :ACR) and Kellgren and Lawrence radiological stage ≥ 2.

Exclusion criteria

  • painful hip or knee prosthesis
  • osteotomy in the past

Treatment and study plan

Hand X-rays

Radiation

Hand X-rays to assess the digital arthrosis

Primary outcomes

  1. Kellgren and Lawrence score

    Time frame: Change at 2 years

    Kellgren and Lawrence score for hip or knee

Secondary outcomes

  1. Harris score

    Time frame: Harris score at 2 years

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Official study title

Study of the Association Between Digital Osteoarthritis and Lower Limb Osteoarthritis (Knee and Hip) in Terms of Severity and Evolution - Khoala Group Ancillary Project / Cohort Khoala

Acronym: Khoala

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Mar 6, 2013
Registry last updated
Mar 31, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.