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Completed

NCT Number: NCT00467233

Study of Acid Peel and Laser for the Treatment of Melasma

The objective of this study is to evaluate laser treatment and acid peel for the treatment of melasma.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Northwestern University Feinberg School of Medicine, Department of Dermatology

Chicago, Illinois, 60611, United States

About this study

The purpose of this study is to evaluate the safety and efficacy of laser treatment and acid peel for the treatment of melasma.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of melasma lesion measuring at least 4 square centimeters.
  • Age 18-75 years.
  • Good health.
  • Willingness and ability to understand and provide informed consent for participation in the study.
  • Ability to communicate with the investigator.
  • Must be willing to forgo other treatment options for melasma during the course of the study.

Exclusion criteria

  • Inability to understand the protocol or to give informed consent.
  • Mental illness.
  • Under 18 years of age and over 75 years of age.
  • Laser treatment in the last 6 months before enrollment.
  • Isotretinoin within the past year.
  • Lidocaine allergy.
  • History of herpes simplex viral infection.
  • Concurrent active disease to facial area (i.e acne).
  • Bleeding disorder.
  • History of abnormal wound healing.
  • History of abnormal scarring.

Treatment and study plan

Laser treatment

Procedure

Laser treatment to half of the face at each study visit

Acid Peel

Procedure

Acid peel to half of the face at each study visit

Primary outcomes

  1. MASI

    Time frame: 20 weeks

Secondary outcomes

  1. Safety

    Time frame: 20 weeks

Sponsors and collaborators

Lead sponsor

Northwestern University

Other

Registry information

Official study title

A Randomized, Rater-blinded, Split-face Comparison of the Efficacy of 30 % Salicylic Acid Peel vs. Q-switched Nd:Yag Laser for the Treatment of Melasma.

Important dates

Study start
2007
Primary completion
2009
Study completion
2009
First posted
Apr 30, 2007
Registry last updated
Dec 2, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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