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NCT Number: NCT03701971

Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis

Many clinical studies have shown the benefit of music therapy in various pathologies, including pain, and it is now established that the latter has a complementary therapeutic interest. Its most frequently identified indications are the fight against acute or chronic pains, the reduction of anxiety, depression and stress, as well as memory disorders such as Alzheimer's disease.

The main modes of action of music therapy involve sensory, cognitive, psychological and behavioral processes that are also found in pruritus.

Pruritus is defined as "an uncomfortable sensation causing the need to scratch. It has similarities with pain but also differences: relief by heat / cold, scratching / withdrawal behavior, localization on the skin, semi-mucous / ubiquitous ... etc.

The pathophysiology also has similarities, pruritus is born at the dermal-epidermal junction at the level of specific cutaneous receptors then follows the classical pathways through a 1st neuron, then the dorsal horn of the spinal cord and a second neuron. At the cerebral level, there is no single center of pruritus but several motor and sensory areas involved.

The similarities suggest that music therapy may have an interest in the management of chronic pruritus, especially since classical treatments (antihistamines, topical corticosteroids) have only partial efficacy in some dermatoses

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Brest University Hospital

Brest, 29609, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least 18 years of age
  • Patient with pruritic dermatosis whatever the etiology (psoriasis, atopic dermatitis, toxiderma, cutaneous lymphoma, chronic urticaria ...)
  • Hospitalized in continuous hospitalization in the Dermatology Department
  • Age of dermatosis ≥ 1 month
  • Pruritus score ≥ 3/10 by numerical evaluation
  • Patient having signed a consent form

Exclusion criteria

  • Patient under the age of 18
  • Major impairment of hearing function
  • Presence of major cognitive disorders
  • Refusal to participate
  • Pregnant or lactating women
  • Institutionalized or emergency patients
  • Patient under legal protection regime
  • Patient not affiliated to the social security system

Treatment and study plan

evaluation of the intensity of pruritus

Other

evaluation of the intensity of pruritus with various questionnaires

Primary outcomes

  1. Variation in the intensity of pruritus

    Time frame: Hour 0 / Hour 1

    Variation in the intensity of pruritus on the digital scale of pruritus

Secondary outcomes

  1. To study the effect of music therapy on the patient's anxiety

    Time frame: Hour 0 / Hour 1

    Completion of questionnaire State-Trait Anxiety Inventory (STAI Y-A)

  2. To study the effect of music therapy according to the etiology of pruritus

    Time frame: Hour 0

    Completion of Questionnaire 5D itch scale

  3. To study the impact of pruritic dermatitis on the quality of life of the patient

    Time frame: Hour 0

    Completion of Questionnaire Itchy Quality of Life

  4. To study the satisfaction of the patients concerning the music session

    Time frame: Hour 1

    Completion of questionnaire PGIC (Patient's Global Impression of Change)

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Official study title

Randomized Prospective Open-label Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis

Acronym: PRURI-MUSIC

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Oct 10, 2018
Registry last updated
Aug 28, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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