Study Evaluating the Association of Antibiotic Measures and Control of Bacterial Resistance

Assess efficacy of piperacillin/tazobactam in reducing the cases of colonization and infection of bacteria.

Completed

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Key information

Conditions

Bacterial Infections Bacterial Infections and Mycoses Infections

Sex eligibility

All sexes

Study type

Observational

About this study

Primarily, this study is designed to assess the efficacy of piperacillin/tazobactam in reducing the cases of colonization and infection of extended-spectrum betalactamases (ESBLs) producing E.coli or K pneumoniae, S aureus methicillin resistant (MRSA) and Enterococcus vancomycin resistant (VRE). Secondly, this study plans to determine the acquisition rate of ESBL producing E Coli or K pneumoniae, methicillin resistant S Aureus (MRSA) and vancomycin resistant Enterococcus spp (VRE), both pre- and post-intervention.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

All patients admitted in ICU will be enrolled (who qualify for treatment).

Treatment and study plan

Primary outcomes

Endpoints will be efficacy of piperacillin/tazobactam in reducing colonization rates and infection of E coli or K pneumoniae, vancomycin resistant enterococcus and methicillin resistant S aureus

Time frame: 8 months

Secondary outcomes

Endpoints will be acquisition and infection rate of ESBL producing E coli or K pneumoniae, vancomycin resistant enterococcus and methicillin resistant S aureus

Time frame: 8 months

Sponsors and collaborators

Lead sponsor

Wyeth is now a wholly owned subsidiary of Pfizer

Industry

Registry information

Official study title

Association of Antibiotic Measures and Control of Bacterial Resistance

Important dates

Study start: 2005
Primary completion: 2007
Study completion: 2007
First posted: Feb 11, 2013
Registry last updated: Feb 13, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed