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OpenTrials
Completed

NCT Number: NCT00700479

Studies on Aldosterone and Vascular Function

A randomized crossover trial to determine the effects of sodium loading and aldosterone infusion on endothelial function in normal subjects.

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Key information

Conditions

Inflammation Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Yale University School of Medicine

New Haven, Connecticut, 06510, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects age >18 years

Exclusion criteria

  • Any chronic medical disease or chronic use of medications

Treatment and study plan

Aldosterone

Drug

4 hour infusion

low or high sodium diet

Dietary Supplement

Placebo

Drug

placebo

Primary outcomes

  1. Flow mediated dilation brachial artery

    Time frame: 0 and 4 hours

Sponsors and collaborators

Lead sponsor

Yale University

Other

Collaborators

  • Pfizer

Registry information

Important dates

Study start
2006
Primary completion
2008
Study completion
2008
First posted
Jun 18, 2008
Registry last updated
Jun 18, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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