Kaohsiung Veterans General Hospital
Kaohsiung City, 81362, Taiwan
NCT Number: NCT05361252
Studies have demonstrated that the rate of change in stroke volume variation (SVV) can be used to determine the volume of body fluids during major abdominal surgery. Anaesthesiologists can use SVV as a guide for the appropriate administration of intraoperative fluids to improve postoperative prognoses. Liver surgery is a major abdominal operation, and the amount of blood lost is typically higher than that during other general abdominal surgeries. Blood loss is positively correlated with the intraoperative fluid infusion volume, and greater blood loss is associated with more postoperative complications. Additionally, comorbid liver disease or cirrhosis can increase the complexity of liver tumour resection, causing difficulty in assessing intravascular volume and determining the appropriate intraoperative infusion volume.
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Notify Me20 year–75 year
All sexes
Interventional
Not applicable
Kaohsiung City, 81362, Taiwan
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
fluid will be guided by value of stroke volume variation
Time frame: From day 1 to day 30 after surgery.
calculate the incidence of postoperative complication within 30 days
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: Examination report on the 1st postoperative day.
Calculate the difference of the perioperative physiological variables
Time frame: up to three days postoperatively
Assessment of postoperative pain scale
Kaohsiung Veterans General Hospital.
Other
Restrictive Versus Liberal Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection: a Prospective Randomised Trial of Perioperative Quality of Care
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