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Completed

NCT Number: NCT05777941

Strength Training With Eccentric Arm-cranking in Para-athletes

The new training device, the eccentric arm-crank, will be examined for its training effects in athletes with a spinal cord injury (SCI) by this project. That the training device can be used in patients with paraplegia in the future, the so-called "testing of the applicability of this concept" will be carried out during this study. Fourteen volunteer, healthy athletes with SCI are first tested for their upper body performance, followed by a training phase over 20 trainings and at the end the performance data is collected again. The training intensity and duration is continuously increased during the training phase.

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Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Swiss Paraplegic Centre

Nottwil, Canton of Lucerne, 6207, Switzerland

About this study

At the beginning, the study design includes a familiarisation appointment with performance tests and training on the eccentric arm-crank device (KREHA). At least one week later, the first test sequence including a maximum strength test (bench press) and a test to determine the anaerobic performance (Wingate test) is conducted. The second test sequence takes place one to three days later. This includes a handgrip strength test, an aerobic endurance test (ramp test on the arm crank ergometer with ergospirometry) and a further familiarisation training on the KREHA. The training phase starts within two weeks after the pre-tests have been completed. There are two to a maximum of three trainings per week. These take 30 to 45 minutes and take place on the KREHA device under the supervision of the study staff. The training phase lasts a maximum of twelve weeks (20 training sessions). The first test sequence is repeated five to eight days after the last workout. The second test sequence takes place at the same time interval as in the pre-tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male or female with traumatic or disease-related SCI
  • age between 18 and 50 years
  • experience in strength training
  • Squad status or at least 4h per week training
  • Biceps/triceps function
  • healthy(study physician)
  • adequately informed and confirmed per signature

Exclusion criteria

  • findings during anamnesis of study physician
  • pregnancy

Treatment and study plan

eccentric arm-cranking training

Other

Over the twenty training sessions, able-bodied participants will exercise on the KREHA device. An arm-crank has to be decelerated, which will be rotated by a prematurely defined revolution rate and training duration. During this intervention a certain power has to be applied. During the whole time of training a continous progression in power and training duration is applied.

Primary outcomes

  1. Upper body Performance

    Time frame: through study completion, an average of 20 weeks

    Peak Power - maximal reached power, generated during the 30sec Wingate arm-crank test

Secondary outcomes

  1. Endurance Oxygen consumption

    Time frame: through study completion, an average of 20 weeks

    VO2peak [ml/min/kg] - Basic Endurance test (Ergospirometry, arm-crank)

  2. Maximal Workload

    Time frame: through study completion, an average of 20 weeks

    Wmax [W] - Basic Endurance test (Ergospirometry, arm-crank)

  3. Upper body Mean Power

    Time frame: through study completion, an average of 20 weeks

    Mean Power [W] - Wingate Test (arm-crank)

  4. Upper body Power - Time to Peak

    Time frame: through study completion, an average of 20 weeks

    Time to Peak [s] - Wingate Test (arm-crank)

  5. Upper body Fatigue Index

    Time frame: through study completion, an average of 20 weeks

    Fatigue Index [%]- Wingate Test (arm-crank)

  6. Upper body Fatigue Slope

    Time frame: through study completion, an average of 20 weeks

    Fatigue Slope [W/s] - Wingate Test (arm-crank)

  7. 1RM bench press

    Time frame: through study completion, an average of 20 weeks

    One Repetition Maximum (1RM) [kg]- bench press

  8. Grip Strength

    Time frame: through study completion, an average of 20 weeks

    Maximal Force that can be generated by pressing hand towards a fist [N]

  9. Upper Arm Circumference

    Time frame: through study completion, an average of 20 weeks

    Circumference of the upper arm is measured with measuring tape

  10. Lower Arm Circumference

    Time frame: through study completion, an average of 20 weeks

    Circumference of the lower arm is measured with measuring tape

Sponsors and collaborators

Lead sponsor

Swiss Paraplegic Research, Nottwil

Network

Registry information

Acronym: KREHA-ParAth

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Mar 21, 2023
Registry last updated
Mar 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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