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Completed

NCT Number: NCT01003353

Strength Training for Chronic Stroke Patients

The study aims to investigate the effects of strength training on maximal strength, walking ability and neural function in chronic stroke patients. The strength training intervention in this study is different to all previous interventions for stroke patients.

Maximal Strength Training (MST) involves weights of up to 90% of the participants 1 repetition maximum and has a focus on the explosive development of force. This study will use these principles for unilateral leg press and plantarflexion exercises. Only 2 previous studies have investigated high intensity strength training for stroke patients and they used intensities of 80% 1RM. Previous MST interventions have shown large increases in strength, rate of force development and this has transferred to improved walking economy.

The investigators predict that MST will give large increases in strength, improved rate of force development (RFD) and walking economy. The investigators expect that better neural function will account for the improvements. This study could provide evidence for the adoption of a completely different method of strength rehabilitation for stroke survivors.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Vascular Diseases

Age range

18 year–67 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Avdeling for ervervede hjerneskader, Klinikk for fysikalsk medisin og rehabilitering, St Olavs Hospital

Trondheim, 7050, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Under 67 years old
  • Suffered from a stroke at least 6 months previously
  • Living in the Trondheim area such that travel costs can be covered by 1500 NOK
  • Must be able to walk, although use of aids is permitted

Exclusion criteria

  • Participants must not have cognitive, visuospatial or comprehension deficits to magnitude such that it interferes with the ability to perform testing and training
  • Participants must be medically unstable (e.g. uncontrollably high blood pressure (140/90), arrythmia, other heart instabilities or other known comorbid diseases)
  • Participants must not be known to be pregnant

Treatment and study plan

maximal strength training

Behavioral

Training will be carried out 3 times a week for 8 weeks. Each session will include a warm up, strength training and warm down. The total time will be approximately 1 hour. The training will consist 2 exercises (leg press and plantarflexion). Participants will train each leg individually with 4 sets of 4 repetitions at 90% of the 1 repetition maximum.

Primary outcomes

  1. Unilateral 1 repetition maximum for leg press and plantarflexion

    Time frame: November 2009-March 2010

Secondary outcomes

  1. Rate of force development in unilateral leg press and plantarflexion

    Time frame: November 2009 - March 2010

  2. Maximal oxygen uptake and walking economy

    Time frame: November 2009 - March 2010

  3. Timed Up and Go Test

    Time frame: November 2009 - March 2010

  4. 4 Step Balance Test

    Time frame: November 2009 - March 2010

  5. V-Wave (using sEMG equipment) of soleus during static plantarflexion

    Time frame: November 2009 - March 2010

  6. Blood lipid profile

    Time frame: November 2009 - March 2010

  7. 6 Minute Walk Test

    Time frame: November 2009 - March 2010

  8. Jump Height of a countermovement jump

    Time frame: November 2009 - March 2010

  9. SF-36 Quality of life questionnaire, Norwegian version

    Time frame: November 2009 - March 2010

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Registry information

Official study title

Maximal Strength Training for Chronic Phase Stroke Patients

Important dates

Study start
2009
Primary completion
2010
Study completion
2010
First posted
Oct 28, 2009
Registry last updated
Jun 25, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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