Virginia Commonwealth University
Richmond, Virginia, 23284, United States
NCT Number: NCT00234598
This study tests whether special oral care provided by nurses to critically ill patients who are on a breathing machine (mechanical ventilator) can help to reduce the build-up of dental plaque on the teeth and reduce the risk of pneumonia.
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Notify Me18 year and older
All sexes
Interventional
Phase 2
Richmond, Virginia, 23284, United States
Pneumonia is the leading cause of death from hospital-acquired infections. Intubation and mechanical ventilation greatly increase the risk of bacterial ventilator associated pneumonia. Growth of potentially pathogenic bacteria in dental plaque of critically ill patients provides a nidus of infection for microorganisms that have been shown to be responsible for the development of Ventilator Associated Pneumonia. Since these organisms are concentrated in dental plaque, removal of organisms from the oral cavity by oral care interventions is a theoretically attractive method to reduce the risk of development of Ventilator Associated Pneumonia. However, evidence-based protocols for oral care of mechanically ventilated patients are not available. Results of the study have the potential to improve nursing care, and to positively affect patient well-being, morbidity, mortality, and health care costs.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Toothbrushing three times per 24 hours without chlorhexidine
Chlorhexidine oral rinse twice per 24 hours without toothbrushing
Toothbrushing three times per 24 hours plus chlorhexidine twice per 24 hours.
Time frame: 7 days
Virginia Commonwealth University
Other
Oral Care Intervention in Mechanically Ventilated Adults
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