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Completed

NCT Number: NCT00752713

Strain-Encoded Magnetic Resonance Imaging in Acute Myocardial Infarction

The aim of the study was therefore to evaluate whether myocardial deformation imaging performed by SENC allows for quantification of regional left ventricular function and is related to transmurality states of infarcted tissue in patients with acute myocardial infarction (AMI).

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Key information

Conditions

Acute Myocardial Infarction

Age range

30 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Heidelberg

Heidelberg, 69120, Germany

About this study

CMR was performed in 38 consecutive patients with AMI 3±1 days after successful reperfusion using a clinical 1.5 Tesla MR-scanner. Ten healthy volunteers served as controls. SENC is a technique that directly measures peak circumferential strain from long-axis views and peak longitudinal strain from short axis views. Measurements were obtained for each segment in a modified 17 segment model. Wall motion and infarcted tissue were evaluated semi-quantitatively from SSFP cine sequences and contrast-enhanced-MR-images and were then related to myocardial strain. Comparison of peak circumferential strain assessed by SENC and MR-tagging was performed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with AMI after successful reperfusion
  • Healthy volunteers in control group

Exclusion criteria

  • No reperfusion

Treatment and study plan

Cardiac MRI

Procedure

cardiac MRI at one time point for group 1 after intervention for group 2 at any time point

Other names: cardiac resonance magnetic imaging

Primary outcomes

  1. Left ventricular function

    Time frame: 01.01.2007 until 01.02.2007

Secondary outcomes

  1. Transmurality

    Time frame: 01.01.2007 until 01.02.2007

Sponsors and collaborators

Lead sponsor

RWTH Aachen University

Other

Collaborators

  • Heidelberg University

Registry information

Official study title

Strain-Encoded Magnetic Resonance Imaging for Evaluation of Left Ventricular Function and Acute Myocardial Infarction

Acronym: 137-2005

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
Sep 15, 2008
Registry last updated
Sep 16, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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