Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy

Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones

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Key information

Conditions

Renal Stone Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Nephrolithiasis Urogenital Diseases Urolithiasis Urologic Diseases

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

services Institute of Medical Sciences

Lahore, Punjab Province, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

single upper ureteric stone
size ranging from 6-15 mm
stones history less than 6 months

Exclusion criteria

Patients with urinary tract infection
multiple ureteric stones,
presence of a ureteric stricture distal to the stone,
previous unsuccessful ESWL,
concomitant use of calcium channel blockers or alpha-adrenergic antagonists
patients with abnormal coagulation profile

Treatment and study plan

Extracorporeal shock wave lithotripsy

Procedure

Extracorporeal shock wave lithotripsy will given to the patients

Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.

Procedure

Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy will be given to the patients

Primary outcomes

stone clearance

Time frame: 4 weeks

Number of patients cleared from ureteric stones

Sponsors and collaborators

Lead sponsor

Services Hospital, Lahore

Other Gov

Registry information

Important dates

Study start: 2018
Primary completion: 2021
Study completion: 2021
First posted: Feb 13, 2023
Registry last updated: Feb 13, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed