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NCT Number: NCT07686913

Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions

This study is evaluating whether Steri-Strips® provide additional benefits when used after cesarean section (C-section) surgery. Steri-Strips are adhesive strips that are commonly placed over a surgical incision to provide support while the wound heals. At our hospital, Steri-Strips are routinely used after C-sections in addition to standard wound closure techniques, although they are not considered part of the standard recommended closure method.

Researchers want to determine whether adding Steri-Strips actually reduces wound complications such as infection, fluid collection under the skin, or reopening of the incision. Previous studies have shown mixed results, with some suggesting little difference in wound healing outcomes while others reported differences in scar appearance. Steri-Strips may also increase costs, add time to the surgery, and occasionally cause skin irritation or allergic reactions.

Participants in this study will be randomly assigned to one of two groups. One group will receive standard cesarean wound closure with Steri-Strips, while the other group will receive standard wound closure without Steri-Strips. Researchers will compare wound healing, complications, patient outcomes, and costs between the two groups.

The goal of this study is to determine whether Steri-Strips improve recovery after cesarean delivery and whether their routine use is beneficial and cost-effective. The findings may help guide future recommendations for cesarean wound care and improve outcomes for patients undergoing C-section delivery.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Riverside University Health System Medical Center

Moreno Valley, California, 92555, United States

Location status: Recruiting

Location contact

Matthew X Perera, DO, MS

CONTACT

[email protected]

8184800214

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female patients age 18 years or older
  • Pregnant patients undergoing cesarean delivery at Riverside University Health System Medical Center (RUHS)
  • Able and willing to provide informed consent

Exclusion criteria

  • Known allergy or hypersensitivity to Steri-Strip™ materials or adhesives
  • Inability or unwillingness to provide informed consent
  • Anticipated inability to complete the 30-day postpartum follow-up evaluation

Treatment and study plan

Steri-Strip™ Skin Closures

Device

Application of Steri-Strip adhesive skin closure strips following standard cesarean section wound closure according to a standardized protocol.

Standard Cesarean Wound Closure

Procedure

Standard skin closure performed following cesarean delivery according to institutional practice.

Primary outcomes

  1. Incidence of Cesarean Section Wound Complications

    Time frame: Within 30 days postpartum

    Composite incidence of postoperative wound complications including surgical site infection, wound seroma, and wound separation/dehiscence following cesarean delivery.

Secondary outcomes

  1. Length of Hospital Stay

    Time frame: From cesarean delivery until hospital discharge (up to 7 days)

    Duration of hospitalization measured from cesarean delivery until discharge.

  2. Readmission Related to Wound Complications

    Time frame: Within 30 days postpartum

    Hospital readmission attributable to wound infection, seroma, or wound separation/dehiscence following cesarean delivery.

  3. Cost of Wound Management

    Time frame: From cesarean delivery through 30 days postpartum

    Comparison of direct healthcare costs associated with wound closure materials and management of postoperative wound complications between study groups.

Study contacts

Contact information is provided by the study sponsor or research team.

Matthew Perera, DO, MS

CONTACT

[email protected]

8184800214

Sponsors and collaborators

Lead sponsor

Riverside University Health System Medical Center

Other

Registry information

Official study title

A Randomized Prospective Trial Comparing Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions

Acronym: STRIP-CS

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 7, 2026
Registry last updated
Jul 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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