Skip to main content
OpenTrials
Completed

NCT Number: NCT04439058

Stellate Ganglion Block Can Cause Enhanced Recovery After Coronary Arteries Bypass Grafting Surgery

The effects of SGB on the cardiovascular system remain controversial since the cardiac sympathetic nerves pass through the stellate ganglion. SGB is expected to have an ameliorative effect on impaired coronary circulation and cardiac function and thus to be well suited to the treatment of angina pectoris and myocardial infarction

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Ischemic Heart Disease Cardiovascular Diseases Heart Diseases Myocardial Ischemia Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Wail Abdelaal

Cairo, 00202, Egypt

About this study

investigators chose left SGB being safer with regards conductivity changes when compared to right SGB, in the present study investigators are trying to examine and compare whether coronary reperfusion in patients undergoing coronary artery bypass grafting who were subject to ultrasound guided left Stellate ganglion block (SGB ) performed in the induction of anesthesia could decrease post cardiopulmonary bypass ischemic changes, pulmonary hypertension and right ventricular dysfunction leading to enhanced recovery.

Place of work: Ain shams university hospitals cardiovascular surgery academy, Cairo, Egypt.

Number and selection of participants:

40 participants, 20 in each group (2 groups).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Ischemic heart disease patients age above 18 years

Exclusion criteria

allergy to LA, severe COPD

Treatment and study plan

ultrasound guided left stellate ganglion block

Other

Stellate Ganglion Block (SGB) has several established clinical indications Under complete aseptic precautions an ultrasound guided left stellate ganglion block was performed. (paratracheal technique ) ( ) The patient was placed in the supine position with the head in the neutral position and slightly extended. An initial scanning was done with the ultrasound to identify the structures in this area.

The US probe was placed at the level of the cricoid cartilage. The transverse process of the sixth cervical vertebra was identified by its prominent anterior tubercle. Also, the longus colli muscle and its overlying prevertebral fascia were sought anterior to the C6 vertebral body and deep to the carotid artery. After skin infiltration with local anesthetic, the needle was inserted from lateral to medial using the in-plane technique. The aim was to inject the local anesthetics deep to the prevertebral fascia and above the longus colli

Primary outcomes

  1. change in heart rate

    Time frame: change in heart rate from base line

    heart rate( bpm )

  2. change in Ejection Fraction

    Time frame: change in Ejection Fraction from base line

    Ejection Fraction(%)

  3. change in blood pressure

    Time frame: change in blood pressure from base line

    MAP, Systemic arterial pressure ( mmHg )

  4. change in cardiac rhythm

    Time frame: change in cardiac rhythm from base line

    incidence of AF or VF(BPM)

Secondary outcomes

  1. effect of preoperative stellate ganglion block on enhanced recovery after coronary arteries bypass grafting surgery

    Time frame: change of troponin level from base line

    measuring troponin level (ng/ml)

Sponsors and collaborators

Lead sponsor

wail abdelaal

Other

Collaborators

  • Ain Shams University

Registry information

Official study title

Preoperative Stellate Ganglion Block Can Cause Enhanced Recovery After Coronary Arteries Bypass Grafting Surgery

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Jun 19, 2020
Registry last updated
Jun 19, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.