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OpenTrials
Completed

NCT Number: NCT07625631

Static Ultrasound Guidance for Radial Arterial Puncture

Radial arterial puncture is a commonly performed procedure in emergency departments for arterial blood gas analysis and invasive hemodynamic monitoring. The conventional palpation technique may be associated with prolonged procedure duration and multiple puncture attempts, particularly in patients with weak arterial pulsation or difficult vascular anatomy.

Ultrasound guidance has been proposed as a method to improve procedural success. This randomized controlled trial aimed to compare the static ultrasound-guided technique with the conventional palpation technique for radial arterial puncture in adult emergency department patients.

The primary outcome was puncture duration. Secondary outcomes included first-attempt success rate, total number of attempts, procedure-related complications, and patient pain scores.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Adem Melekoglu, MD

Istanbul, Kağıthane, 34413, Turkey (Türkiye)

About this study

Radial arterial puncture is frequently performed in emergency departments for arterial blood gas sampling and invasive arterial pressure monitoring. Although the conventional palpation technique is widely used, procedural failure, prolonged puncture duration, and repeated attempts remain common problems, especially in patients with difficult vascular access.

Ultrasound-guided vascular access techniques have demonstrated improved success rates in several vascular procedures. However, evidence regarding the effectiveness of the static ultrasound-guided method for radial arterial puncture in emergency department settings remains limited.

This prospective randomized controlled trial was conducted in the emergency department of University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital. Adult patients requiring radial arterial puncture were randomly assigned to either the static ultrasound-guided group or the conventional palpation group.

In the static ultrasound-guided group, the radial artery location was identified using ultrasonography prior to skin puncture, and the puncture site was marked externally. In the conventional group, arterial puncture was performed using anatomical landmarks and palpation alone.

The primary outcome of the study was puncture duration. Secondary outcomes included first-attempt success, total number of puncture attempts, procedure-related complications, and patient-reported pain scores.

The study aimed to evaluate whether the static ultrasound-guided technique could improve procedural efficiency and success compared with the conventional palpation technique in emergency department practice.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients aged 18 years and older
  • Patients requiring radial arterial puncture in the emergency department
  • Patients who provided informed consent

Exclusion criteria

  • Patients younger than 18 years
  • Known vascular abnormalities or previous vascular surgery involving the puncture site
  • Local infection or skin lesion at the puncture site
  • Hemodynamic instability requiring immediate intervention
  • Inability to provide informed consent
  • Previous enrollment in the study

Treatment and study plan

Static Ultrasound-Guided Radial Arterial Puncture

Procedure

Static ultrasound guidance was used to identify and externally mark the radial artery location prior to arterial puncture.

Conventional Palpation Technique

Procedure

Radial arterial puncture was performed using anatomical landmarks and palpation without ultrasound guidance

Primary outcomes

  1. Puncture Duration

    Time frame: Immediately after the procedure

  2. Puncture Duration

    Time frame: At completion of the arterial puncture procedure or after a maximum of three puncture attempts

    Time required to successfully complete radial arterial puncture, measured from skin contact of the needle to successful arterial blood aspiration.

Secondary outcomes

  1. First-Attempt Success Rate

    Time frame: During the procedure

    Successful radial arterial puncture achieved on the first needle insertion attempt.

Other outcomes

  1. Pain Score

    Time frame: Immediately after completion of the arterial puncture procedure

    Patient-reported procedural pain measured immediately after arterial puncture using a 10-point Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates the worst imaginable pain.

Sponsors and collaborators

Lead sponsor

Sisli Hamidiye Etfal Training and Research Hospital

Other

Registry information

Official study title

Static Ultrasound-Guided Versus Conventional Palpation Techniques for Radial Arterial Puncture in the Emergency Department: A Randomized Controlled Trial

Acronym: STATIC-US

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jun 4, 2026
Registry last updated
Jun 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.