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NCT Number: NCT07082036

Stability of Hemiparetic Patients During a Daily Complex Task

Among the repercussions of hemiparesis following stroke, disturbed stability is responsible for a high risk of falls. Picking up objects from the ground, frequently trained in rehabilitation due to its risk of falling and its frequency in daily life, is a task requiring balance. To date, however, it has been little studied. We suggest that stability conditions the asymmetry adopted by patients. We hypothesise that asymmetric support at the expense of the paretic lower limb provides better stability during an unstable functional task (picking up an object from the ground) compared with the symmetrical support traditionally imposed in rehabilitation.

Postural control involves stability (maintaining balance despite constraints) and orientation (posture adopted, such as the distribution of supports). Hemiparetic patients show a lack of stability and, with regard to orientation, an asymmetry in the distribution of body weight to the detriment of the paretic limb. Symmetrisation of weight distribution has been one of the predominant concepts in rehabilitation.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Raymond Poincaré - APHP

Garches, 92380, France

Location status: Recruiting

About this study

To analyse the stability of hemiparetic stroke patients when picking up an object on the ground in a spontaneous condition compared with a condition of imposed support symmetry.

To analyse and compare the stability, spontaneous symmetry and duration of picking up the object in a complex situation (distant target) compared with the near target in stroke patients and healthy subjects.

To explore strategy and performance of picking up the object regarding clinical outcomes (falls, sensori-motor impairments, balance..) To compare strategy of patients with right and left stroke.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All:

Male or female ≥ 18 years

For patients :

  • Haemiparesis after a single unilateral hemispheric Stroke.
  • Stroke ≥ 6 months
  • Asymmetry of support between the 2 lower limbs (distribution of body weight) in a standing position at the expense of the paretic lower limb > 10%.
  • Able to stand alone, without technical aids or equipment, with feet the width of the pelvis
  • Able to pick up an object from the ground alone (minimum score 3/4 item 9 of the Berg Balance Scale).
  • Patient informed and having signed a consent form

For healthy subjects:

  • Similar characteristics (in terms of sex, age range and BMI class) to those of one of the patients already included.

Exclusion criteria

-

Treatment and study plan

Primary outcomes

  1. stability parameter: the range of the medio-lateral centre of pressure during the object picking up task

    Time frame: at baseline

    Two forceplate platforms. 3 trials for each condition

Secondary outcomes

  1. Velocity of the centre of pressure

    Time frame: at baseline

    Mean velocity and in each place, in mm/s, obtained with forceplat plateforms under feet of participants during the object picking up task.

  2. Ellipse area of the centre of pressure

    Time frame: at baseline

    With 95% confidence, in mm², obtained with forceplat plateforms under feet of participants during the object picking up task

  3. Range of the centre of pressure

    Time frame: at baseline

    Range in antero-posterior plane, in mm, obtained with forceplat plateforms during the object picking up task

  4. Percentage of weight bearing

    Time frame: at baseline

    Under each lower limb, in %, obtained with forceplat plateforms during the object picking up task

  5. Kinematics parameters

    Time frame: at baseline

    range of movements of trunk, pelvis and lower limbs (hip, knee, ankle), in degrees, obtained with the optoelectronic system during the object picking up task

  6. Questionnaires : Confidence perception and stability perception during the object picking up task

    Time frame: at baseline

    On a visual scale 0 (no confidence) to 10 (perfect confidence)

  7. Clinical scales - Berg balance scale

    Time frame: at baseline

  8. Clinical scales-Medical Research Council

    Time frame: at baseline

  9. Clinical scales-Modified Ashworth

    Time frame: at baseline

  10. Clinical scales-Nottingham Sensory Assessment

    Time frame: at baseline

  11. Clinical scales -Neglect and lateropulsion scale

    Time frame: at baseline

  12. Cognitive scale : Batterie Rapide d'Efficience Frontale

    Time frame: at baseline

  13. Activities-Specific Balance Confidence

    Time frame: at baseline

  14. Functional reach test

    Time frame: at baseline

    In cm

Study contacts

Contact information is provided by the study sponsor or research team.

Céline Bonnyaud, PhD

CONTACT

[email protected]

+ 33 01 71 14 49 21

Sponsors and collaborators

Lead sponsor

Assistance Publique - Hôpitaux de Paris

Other

Registry information

Official study title

Study of the Stability of Post-stroke Hemiparetic Patients During a Task Involving Picking up an Object on the Ground. Reflection Questioning the Conventional Rehabilitation of These Patients

Acronym: HemiSym

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jul 24, 2025
Registry last updated
Jul 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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