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Completed

NCT Number: NCT05013021

Sprint Interval Training on the Endurance, Strength and Velocity Capacities of Healthy Sedentary Subjects

The present study aims to analyse first, the acute effects generated by a single bout of Sprint Interval Training (SIT) and, secondly, the effects of a long-term intervention on sedentary participants.

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Key information

Conditions

Sedentary Behavior Behavior

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHU de Saint-Etienne

Saint-Etienne, 42055, France

About this study

The main goal is to determine the optimal dose of high-intensity exercise that enhances the best physiological adaptations.

The cumulative effects of SIT, will be assessed by a series of measures placed throughout the time-course (before, after the 1st , the 2nd and the 3rd block of SIT). Those measures consist of physiological measurements (VO2max), neuromuscular capacities (force-velocity profile) the autonomic nervous system responses (heart rate variability) and blood markers (lactate, Creatine phosphoKinase (CK), cytokinases, µRNA). Acute effects will be measured in the familiarisation sessions (after short (8 sprints) and long (14 sprints) sets) by performing a battery of neuromuscular, perceptual, and autonomic nervous system tests before and after the single session of SIT.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • untrained healthy (less than 2 hours of sport per week)
  • free from muscular, bone or joint injuries
  • free from neurologic disease

Exclusion criteria

  • taking neuroactive substances that can alter corticospinal excitability
  • Heart or respiratory failure.
  • Subjects who have taken corticosteroids within 3 months (inhalation, infiltration or history of corticosteroid therapy).
  • Pregnant woman
  • Subject under guardianship

Treatment and study plan

Sprint Interval Training

Other

The Sprint Interval Training (SIT) training consists of 3 successive blocks of 5 training sessions each. The sessions are 24 to 48 hours apart.

. One block lasts two weeks. After the end of one block, the following block begins the day after.

The Sprint Interval Training lasts 6 weeks.

Each session consists of a series of sprints, the number of which varies from 8 to 14. Thus a session will last from 30 to 45 min approximately

So, the time frame of this study is Baseline, Block 1, Block 2 and Block 3 (Not in day or week or month)

Primary outcomes

  1. oxygen uptake (VO2max) - ml/min/kg

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    consumption oxygen uptake (VO2max) measured on a cycle ergometer

    The main objective is to determine at which time frame of sprint interval training blocks, the endurance performance (VO2max) is best.

Secondary outcomes

  1. Maximum power (W)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    It is measured thanks to the force-speed profile using two sprints of 7s with braking forces of 0 , 4 and 0.7 N.kg-1 respectively.

  2. Maximum theoretical force (N.m)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    It is measured thanks to the force-speed profile using two sprints of 7s with braking forces of 0 , 4 and 0.7 N.kg-1 respectively.

  3. Maximum theoretical speed (m/s)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    It is measured thanks to the force-speed profile using two sprints of 7s with braking forces of 0 , 4 and 0.7 N.kg-1 respectively.

  4. Maximum isometric force (N.m)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    It is measured by means of a voluntary maximum contraction test in which the maximum force generated voluntarily is compared to that voluntarily generated force will be compared to that evoked using electrical stimulation of the femoral nerve.

  5. heart rate variability (HRV)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

  6. Lactate (mmol/l)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    Blood sample

  7. Cytokines (pg/ml)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    Blood sample

  8. Creatine Kinase (UI/l)

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    Blood sample

  9. muscle microRNA

    Time frame: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

    Blood sample

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne

Other

Registry information

Official study title

Sprint Interval Training (SIT) on the Endurance, Strength and Velocity Capacities of Healthy Sedentary Subjects

Acronym: BénéfiSIT

Important dates

Study start
2021
Primary completion
2023
Study completion
2023
First posted
Aug 19, 2021
Registry last updated
Jul 19, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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