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OpenTrials
Completed

NCT Number: NCT02804867

Spot Depression Study

This study aims to identify signs of depression and bipolar disorder by measuring changes of certain molecules (biomarkers) that can be detected in dried blood spots. Our goal is to use these biomarkers to develop a diagnostic test to enable early treatment, which can lead to better patient outcomes.

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Key information

Conditions

Bipolar Disorder Bipolar and Related Disorders Depressive Disorder Mental Disorders Mood Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Jordan Ramsey

Cambridge, Cambridgeshire, CB2 1QT, United Kingdom

About this study

Bipolar disorder and major depression are serious mental health conditions that have a devastating impact on patients, their families and friends, and society. Currently, no laboratory test exists for these disorders. We are trying to develop a molecular test based on blood spots (small spots of blood obtained from patients' fingertips that have been dried on special paper). Volunteers take part by filling out the questionnaire at www.spot-depression.org. They may then be selected to provide a dried blood spot, which can be collected at home using a kit that will be mailed to their address.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Residing in the United Kingdom
  • Over 18 years of age

Exclusion criteria

  • Pregnant or breastfeeding
  • Presence of blood-borne infection

Treatment and study plan

Online questionnaire and self-administered blood spot

Procedure

Primary outcomes

  1. Comparison of protein concentrations in dried blood spots between patient groups and controls

    Time frame: Baseline (at enrollment); no follow-up

  2. Assessment of classification accuracy of protein concentrations in dried blood spots for distinguishing between bipolar disorder and depression

    Time frame: Baseline (at enrollment); no follow-up

Sponsors and collaborators

Lead sponsor

University of Cambridge

Other

Registry information

Official study title

A Blood Test to Identify Persons at Risk of Developing Depression or Bipolar Disorder

Important dates

Study start
2016
Primary completion
2016
Study completion
2016
First posted
Jun 17, 2016
Registry last updated
Feb 23, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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