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Active, Not Recruiting

NCT Number: NCT07449663

SPORT-SPECIFIC HIIT IN ELITE KICKBOXERS

This study examines how sport-specific high-intensity interval training (HIIT) affects the body in elite kickboxers.

Participants are randomly assigned to either a HIIT training group or a control group. The HIIT group performs supervised sport-specific training for eight weeks, while the control group continues their usual training. Blood samples are collected before and after the training period.

The main goal of this study is to determine whether HIIT changes levels of exercise-related proteins such as apelin and irisin. These proteins may reflect how the body adapts to intense training.

The findings may help researchers and coaches better understand the effects of high-intensity training and may support the development of safer and more effective training programs for athletes.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Adiyaman University Faculty of Sport Sciences

Adıyaman, 02040, Turkey (Türkiye)

About this study

This randomized controlled trial investigates the effects of sport-specific high-intensity interval training (HIIT) on biochemical markers related to exercise adaptation in elite kickboxers.

High-intensity interval training is widely used in combat sports because it reflects the intermittent high-intensity nature of competition. Exercise-induced proteins such as apelin and irisin are considered potential biomarkers of physiological adaptation to training. However, biochemical responses to sport-specific HIIT in elite combat athletes remain insufficiently understood.

Participants are elite male kickboxers aged 18-30 years with at least five years of training experience. Participants are randomly assigned to either an experimental group performing sport-specific HIIT or a control group continuing their regular training routines.

The HIIT program lasts eight weeks and includes supervised training sessions five days per week at an intensity of approximately 85-95 percent of maximum heart rate. The control group continues their usual technical and tactical kickboxing training without participation in the structured HIIT program.

Blood samples are collected at baseline and after completion of the eight-week intervention period. Serum concentrations of apelin and irisin are assessed as primary outcomes. Secondary outcomes include leptin, interleukin-6, and selected hematological parameters.

The purpose of this study is to evaluate biochemical adaptations to sport-specific HIIT and to identify potential biomarkers of training adaptation in elite athletes. The findings may contribute to improved athlete monitoring and the development of evidence-based training programs.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male elite kickboxers aged 18 to 30 years
  • At least five years of regular kickboxing training experience
  • Active participation in kickboxing training
  • Ability to complete the training program

Exclusion criteria

  • Serious injury within the previous six months
  • Presence of chronic or cardiometabolic disease
  • Regular use of medications or ergogenic supplements
  • Tobacco or alcohol use
  • Inability to complete the training program

Treatment and study plan

Sport-Specific High-Intensity Interval Training

Behavioral

Participants perform supervised sport-specific high-intensity interval training five days per week for eight weeks. Training intensity is maintained at approximately 85-95 percent of maximum heart rate. The program consists of repeated high-intensity exercise intervals interspersed with active recovery periods and is designed to reflect the physiological demands of competitive kickboxing.

regular training

Behavioral

Participants continue their usual kickboxing training routines without participation in the structured HIIT program.

Primary outcomes

  1. Serum Apelin Concentration

    Time frame: Baseline and Week 8

    Serum apelin concentration measured using enzyme-linked immunosorbent assay (ELISA).

Sponsors and collaborators

Lead sponsor

Adiyaman University

Other

Registry information

Official study title

SPORT-SPECIFIC HIGH-INTENSITY INTERVAL TRAINING INDUCES SELECTIVE APELIN AND IRISIN RESPONSES IN ELITE KICKBOXERS: A RANDOMIZED CONTROLLED TRIAL

Acronym: HIIT-KICK

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 4, 2026
Registry last updated
Mar 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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