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OpenTrials
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NCT Number: NCT03920969

Sport and Self Esteem in Patients Living With HIV

Adapted athletic activity has shown benefits in patients with certain chronic diseases, including improving fatigue and pain in patients with cancer, and improving the symptoms of severe depression.

Among Patients Living with Human Immunodeficiency Virus (PLHIV), sport appears to be less common than for people who do not live with HIV. In fact, 44% of PLHIV in a Swiss cohort (10,500 patients) were inactive in 2014, whereas this percentage was 26% in the general population in Switzerland. We did not find any French data on the prevalence of sports activity among PLHIV.

The benefits of sport in PLHIV are numerous: meta-analyzes on interventional studies of aerobic and resistance exercises show a significant improvement in maximum oxygen consumption, muscle strength, percentage of body fat, quality of life and symptoms of depression. An improvement in cognitive function was noted in a randomized study. An Iranian randomized study of 2017 showed an improvement in the CD4 count, after 8 weeks of resistive exercise, but two meta-analyzes of 2016 and 2017 did not find a significant change in CD4 or viral load with physical exercise.

On the other hand, several studies have shown that sports practice improves self-esteem. In addition, an Australian randomized study in 2006 showed an improvement in self-efficacy in PLHIVs after a six-month exercise (aerobic and resistance) program. Furthermore, self-esteem (defined as positive self-esteem) is a factor facilitating adherence to antiretroviral therapy.

The objective of this descriptive study is to evaluate the prevalence of sports activity in a French adult population infected with HIV and to seek an association with self-esteem. In addition, the investigators will look for an association between sport and fatigue, pain, sleep, lymphocyte T CD4 cell levels, viral load.

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patient with HIV
  • aged over 18
  • Patient followed by a physician in one of the participating centers of the Regional coordination of the fight against HIV infection (COREVIH) Pays de la Loire

Exclusion criteria

  • Refusal or unability to answer the self-questionnaire.
  • Patient Under guardianship

Treatment and study plan

Sports activity

Behavioral

Evaluation of physical activity using the International Physical Activity Questionnaire (IPAQ) short version.

Primary outcomes

  1. Assessment of self-esteem according to the sport activity of PLHIV

    Time frame: six months

    Prevalence of self-esteem (Rosenberg questionnaire) among PLHIV, according to sport activity

Secondary outcomes

  1. Description of the sporting activity of an adult HIV population

    Time frame: Six months

    Number and frequency of characteristics related to sports activity

  2. Description of factors associated with sports activity: fatigue

    Time frame: Six months

    Prevalence of fatigue symptoms

  3. Description of factors associated with sports activity: pain

    Time frame: Six months

    Prevalence of pain symptoms

  4. Description of factors associated with sports activity: sleep

    Time frame: Six months

    Prevalence of sleep disorders

  5. Search for a correlation between physical activity and HIV activity

    Time frame: 6 months

    Measure of the correlation between the measured physical activity and CD4 levels and HIV load.

Sponsors and collaborators

Lead sponsor

Centre Hospitalier le Mans

Other

Collaborators

  • COordination REgionale de lutte contre les IST et le VIH (COREVIH) des Pays de la Loire
  • Centre Hospitalier de Cholet
  • Hospital, La Roche sur Yon
  • Hospital, Saint Nazaire
  • Nantes University Hospital
  • University Hospital, Angers

Registry information

Official study title

Assessment of Self-esteem According to the Practice of a Sport Activity in a Population of Adults Living With HIV

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Apr 19, 2019
Registry last updated
Mar 9, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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