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OpenTrials
Completed

NCT Number: NCT03609411

Splenectomy During Whole Liver Transplantation

Indications for splenectomy during whole liver transplantation remain controversial and splenectomy is often avoided because of common complications. The objective is to evaluate specific complications of these combined procedures.

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Key information

Conditions

End Stage Liver Disease Digestive System Diseases Hepatic Insufficiency Liver Diseases Liver Failure

Age range

16 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hopital de la Croix-Rousse

Lyon, France

About this study

Data on patients who underwent splenectomy during liver transplantation were retrospectively analyzed . Participants underwent splenectomy as part of routine medical care. Patients undergoing simultaneous liver transplantation and splenectomy were matched to a non-splenectomy group.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing liver transplantation between 1994 and 2013

Exclusion criteria

  • Data from living donor patients, split liver transplantation, patients with pre- or post-operative splenectomy in medical history, and patients under 16 years were excluded from analysis

Treatment and study plan

splenectomy

Procedure

Splenectomy was performed after hepatectomy, in an extra-hilar manner with manual ligation of splenic vessels.

Other names: Liver transplantation

Primary outcomes

  1. 3-month post-operative mortality

    Time frame: At 3 months post surgery

Secondary outcomes

  1. Post-operative morbidity

    Time frame: 3 months post surgery

    Incidence of portal-vein thrombosis within 3 months post liver transplantation

  2. One-year mortality

    Time frame: One year after surgery

  3. Mortality at 5 years

    Time frame: Five years after surgery

Sponsors and collaborators

Lead sponsor

Hospices Civils de Lyon

Other

Registry information

Important dates

Study start
2015
Primary completion
2017
Study completion
2017
First posted
Aug 1, 2018
Registry last updated
Aug 1, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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