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NCT Number: NCT06289816

Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes

This retrospective cohort study examines the effectiveness of minimally invasive spleen-preserving surgeries compared to total splenectomy for treating primary splenic hydatidosis in Jordan. Covering 18 patients from January 2015 to June 2021, the research highlights similar recurrence rates between both surgical approaches, emphasizing the benefits of spleen preservation in maintaining immune function and reducing septic risks, particularly in pediatric patients.

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Key information

Conditions

Spleen-Preserving Surgery Cestode Infections Disease Attributes Echinococcosis Echinococcus Granulosus Infection Helminthiasis Hydatid Disease Infections Minimally Invasive Surgery Parasitic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Recurrence

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Anas Aljaiuossi

Irbid, 22110, Jordan

About this study

The study delves into a detailed analysis of 18 cases of primary splenic hydatid cysts treated through spleen-preserving surgeries-laparoscopic partial splenectomy, cystectomy, and cyst deroofing-augmented by albendazole therapy. It presents a comprehensive comparison based on patient demographics, symptoms, surgical details, and outcomes, including complications and recurrence rates. Findings reveal no significant statistical difference in recurrence rates between spleen-preserving methods and total splenectomy, suggesting the viability of less invasive approaches for managing this condition effectively while preserving spleen functionality and minimizing post-operative complications. The study underlines the need for individualized treatment plans and further research with larger cohorts.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult patients (age 14 years or older).
  • Diagnosed exclusively with primary, non-recurrent splenic hydatid cysts.

Exclusion criteria

  • Children under 14 years of age.
  • Patients in late pregnancy.
  • Individuals with recurrent cysts.
  • Cases with extra-splenic involvement.
  • Patients with less than two years of postoperative follow-up.

Treatment and study plan

Minimally Invasive Surgery

Procedure

Minimally Invasive Surgery : Laparoscopic partial splenectomy, cystectomy, and cyst deroofing.

Primary outcomes

  1. Incidence of Postoperative Short-Term Complications

    Time frame: Up to 1 month post-operation

    The measure focuses on the incidence and nature of short-term complications following spleen-preserving surgeries compared to total splenectomy. Short-term complications may include infection, bleeding, or any other immediate post-surgical issues that impact recovery.

  2. Incidence of Postoperative Long-Term Complications

    Time frame: Up to 2 years post-operation

    This measure assesses the long-term complications associated with spleen-preserving surgeries versus total splenectomy. Specifically, it examines the recurrence of hydatid cysts as a significant long-term complication.

Sponsors and collaborators

Lead sponsor

Yarmouk University

Other

Registry information

Official study title

Minimally Invasive Spleen Preserving Surgery to Treat Primary Splenic Hydatidosis: Short and Long Term Outcomes: A Cohort Study

Important dates

Study start
2015
Primary completion
2021
Study completion
2021
First posted
Mar 4, 2024
Registry last updated
Mar 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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