Skip to main content
OpenTrials
Completed

NCT Number: NCT06768333

Speed of Glucose Absorption During Exercise

The purpose of this study is to look at how fast commercially available supplements containing carbohydrates can get into the bloodstream during repeated sprint cycles. This will build from a pervious study where the investigators tested these supplements on healthy participants during a resting oral glucose tolerance trial. The investigators will be testing three supplements, namely Voom Pocket Rocket, SIS Go Isotonic Energy Gel, and Maurten Gel 160. Each participant will complete all three conditions, consuming one of each supplement at random per condition. The study requires participation from male and female runners, cyclists and triathletes who are aged between 18-40.

Each visit will take approximately 1 hour, and three experimental visits per participant. The study will involve frequent blood sampling and the continuous monitoring of gas exchange (oxygen/carbon dioxide). Blood sampling via cannulation will be used to analyse the lactate, glucose, and electrolyte content of the blood. Gas exchange will measure the oxygen breathed in and carbon dioxide breathed out throughout the exercise.

The investigators plan to carry out the study on 10 participants who will be a mix of male and female runners, cyclists and triathletes.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Nutrition Healthy

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Lancaster University

Lancaster, Lancashire, LA1 4AT, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Aged between 18-40 years
  • Male or female
  • Tier 2 athletes - local level representation, training ~ 3 times per week, training with a purpose to compete, identify with a specific sport, limited skill development (McKay et al., 2021)

Exclusion criteria

  • Allergies to any listed ingredients on any supplements.
  • Diabetes (type 1 or 2)
  • Any medical conditions
  • Smokers
  • Any injury that would prevent them from exercising
  • Anyone using drugs or medication (not including contraception)
  • Anyone consuming alcohol within 24 hours of the study
  • Exercise must be restricted within 24 hours of the study
  • Caffeine must not be consumed within 24 hours of testing as it can significantly enhance carbohydrate oxidation rates (Yeo et al., 2005)
  • Diets including high-carbohydrate-low-fat (HCLF), low-carbohydrate-high-fat (LCHF), ketogenic, and/or glycogen manipulation diets (Rauch et al., 2022)

Treatment and study plan

45 grams Voom Pocket Rocket Electro Energy

Dietary Supplement

Participants will be required to consume 45 grams (in carbohydrates) of the Voom Pocket Rocket Electro Energy on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

45 grams Maurten Gel 160

Dietary Supplement

Participants will be required to consume 45 grams (in carbohydrates) of the Maurten Gel 160 on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

45 grams SIS Go Isotonic Energy Gel

Dietary Supplement

Participants will be required to consume 45 grams (in carbohydrates) of the SIS Go Isotonic Energy Gel on one of the three experimental visits. Participants will have blood glucose, blood lactate, and electrolytes sampled throughout five 15-second repeated cycling intervals interspersed with 3 minutes active recovery. Gas exchange will also be monitored throughout the 1-hour study visit.

Primary outcomes

  1. Blood Glucose

    Time frame: Blood glucose measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recovery

    Frequent blood sampling for blood glucose (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser

  2. Blood Lactate

    Time frame: Blood lactate measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recovery

    Frequent blood sampling for blood lactate (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser

  3. Gas Exchange

    Time frame: Gas exchange will be measured continuously throughout the 20 minutes of exercise, starting at the warmup

    Gas exchange measured throughout each 20 minute exercise via a Cortex Metalyzer

Secondary outcomes

  1. Blood electrolyte content

    Time frame: Blood electrolyte measures will be taken 35 minutes after consuming the supplement(s) (baseline), after the 3 minute warmup, and then after every 15 second sprint and every 3 minute period of active recovery

    Frequent blood sampling for electrolyte concentrations of the blood (sodium, potassium, chloride, calcium) (1ml after every stage of both sprint cycling and active recovery) followed by analysis in the Biosen Analyser

  2. Rate of Percieved exertion (RPE)

    Time frame: RPE will be measured at the end of the warmup and the end of the final sprint stage

    Participants will report their RPE using the Borg Scale to report how hard they are finding the exercise. This will be done after the warm-up and after the final sprint.

  3. Gastrointestinal (GI) Discomfort Questionnaire

    Time frame: GI Discomfort will be measured 5 minutes before and 5 minutes after exercise

    Participants will complete a GI discomfort questionnaire 5 minutes before starting exercise and at the end of exercise

Sponsors and collaborators

Lead sponsor

Lancaster University

Other

Registry information

Official study title

The Need for Speed: Comparing the Speed of Glucose Absorption During Repeated Sprint Cycling

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 10, 2025
Registry last updated
Mar 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.