Spectral Optical Coherence Tomography Findings in Patients With Ocular Toxoplasmosis

Ocular toxoplasmosis is the most common cause of infectious uveitis worldwide. The diagnosis of ocular toxoplasmosis is primarily clinical when it is a typical presentation .With an atypical presentation in the fundus, parasitological diagnosis is a decisive contribution, as well as multimodal imaging. We investigate on vitreal, retinal, and choroidal morphologic changes in active and scarred toxoplasmosis lesions using swept source optical coherence tomography.

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Key information

Conditions

Ocular Toxoplasmosis Coccidiosis Eye Diseases Eye Infections Eye Infections, Parasitic Infections Parasitic Diseases Protozoan Infections Toxoplasmosis Toxoplasmosis, Ocular Uveal Diseases Uveitis

Sex eligibility

All sexes

Study type

Observational

About this study

A retrospective analysis of patients diagnosed with ocular toxoplasmosis was conducted. The patients were examined at ophthalmology service of Farhat Hached Hospital in Sousse Tunisia between January 2002 and December 2017. Complete ophthalmologic examination and OCT were done at the initial visit and during follow-up.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

all patients hospitalized for ocular toxoplasmosis.

Exclusion criteria

patients with non active ocular toxoplasmosis

Treatment and study plan

Spectral optical coherence tomography

Diagnostic Test

Swept-source optical coherence tomography (SS-OCT) is the latest milestone in retinal and choroidal imaging. Because its wavelength of 1050 nm, which is superior to the 840 nm of spectral domain optical coherence tomography (SD-OCT), it is able to overcome ocular opacities such as cataracts and vitritis, wich allows retinal and choroidal visualization of eyes whose fundus is not clearly visible. Consequently , SS-OCT allows visualization of the retinal and choroidal vascular networks, even in eyes with medium opacity

Primary outcomes

number of prticipant affected with ocular toxoplasmosis

Time frame: up to one year

patient diagnosed having ocular toxoplasmosis

Sponsors and collaborators

Lead sponsor

Université de Sousse

Other

Registry information

Official study title

Spectral Optical Coherence Tomography Findings in Patients With Ocular Toxoplasmosis : a Retrospective Study

Important dates

Study start: 2002
Primary completion: 2017
Study completion: 2018
First posted: Jan 6, 2020
Registry last updated: Jan 27, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed