SPECT/CT in the Diagnosis of Dementia

Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.

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Key information

Conditions

Dementia Brain Diseases Central Nervous System Diseases Disease Mental Disorders Nervous System Diseases Neurocognitive Disorders Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

All sexes

Study type

Observational

Primary location

Kuopio University Hospital

Kuopio, 70211, Finland

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(one of these):

healthy control
mild cognitive impairment (recruited from a population based data)
clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion criteria

unable to be scanned with SPECT/CT

Treatment and study plan

Primary outcomes

Final diagnosis

Time frame: 4 years

(1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses

Sponsors and collaborators

Lead sponsor

Kuopio University Hospital

Other

Collaborators

University of Eastern Finland

Registry information

Acronym: DEMSPET

Important dates

Study start: 2006
Primary completion: 2010
Study completion: 2010
First posted: Apr 28, 2010
Registry last updated: Apr 28, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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