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Completed

NCT Number: NCT01968252

Speckle-tracking Tricuspid Annular Plane Systolic Excursion

The study is designed to validate the use of speckle-tracking echocardiography to measure tricuspid annular plane systolic excursion as a measurement of right ventricular function during transesophageal echocardiography.

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Key information

Age range

19 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Unversity of Nebraska Medical Center

Omaha, Nebraska, 68198, United States

About this study

  • Use of speckle-tracking echocardiography to validate tricuspid annular plane systolic excursion measurements with transesophageal echocardiography.
  • This study intends to validate the use of speckle-tracking echocardiography to measure the distance the tricuspid annulus moves during the systolic phase. The guideline articles regarding right ventricular function suggest m-mode measurements from the transthoracic approach and the same measurements may underestimate the actual distance on transesophageal echocardiography. This speckle-tracking technology will allow this distance to be measured despite its often non-parallel motion to the ultrasound beam, which otherwise limits the reliability of the valve recorded.
  • All subjects undergoing a planned surgical procedure in which the use of transesophageal echocardiography would be used regardless for their management.
  • No interventions, only evaluation of the measurements obtained with transthoracic echocardiography compared to transesophageal echocardiography.
  • No follow-up, study will be completed at the time of image acquisition.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All subjects who are scheduled to undergo general anesthesia and concurrently will be managed with intraoperative transesophageal echocardiography will be included in potential subjects.

Exclusion criteria

  • Subjects who do not have adequate transesophageal and/or transthoracic imaging windows to allow for accurate analysis of tricuspid annular motion.

Treatment and study plan

Concurrent TTE and TEE

Other

All subjects will undergo both transthoracic echocardiography and transesophageal echocardiography to compare the results of measurements obtained from both imaging locations.

Primary outcomes

  1. Speckle-tracking derived tricuspid annular plane systolic excursion with transesophageal echocardiography

    Time frame: 1 hour

    Speckle-tracking derived tricuspid annular plane systolic excursion with transesophageal echocardiography

Secondary outcomes

  1. M-mode derived tricuspid annular plane systolic excursion with transesophageal echocardiography

    Time frame: 1 hour

    M-mode derived tricuspid annular plane systolic excursion with transesophageal echocardiography

  2. M-mode derived tricuspid annular plane systolic excursion with transthoracic echocardiography

    Time frame: 1 hour

    M-mode derived tricuspid annular plane systolic excursion with transthoracic echocardiography

  3. Speckle-tracking derived tricuspid annular plane systolic excursion with transthoracic echocardiography

    Time frame: 1 hour

    Speckle-tracking derived tricuspid annular plane systolic excursion with transthoracic echocardiography

Sponsors and collaborators

Lead sponsor

University of Nebraska

Other

Registry information

Official study title

Validation of Speckle-tracking Echocardiography Measurements of Tricuspid Annular Plane Systolic Excursion During Transesophageal Echocardiography

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Oct 23, 2013
Registry last updated
Sep 1, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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