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Completed

NCT Number: NCT04286022

Specific Neurotechnical Strength Training (NeuroTraining)

This study aims to apply a novel study methodology using high density electromyography (HDEMG) to know what are the mechanisms underlying the structural and functional changes obtained by two different training methods, commonly used, facilitating their understanding, study and subsequent application according to specific needs.

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Key information

Conditions

Neuromuscular Adaptations

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Health Science School , University of Malaga

Málaga, 29009, Spain

About this study

Different training methodologies have previously shown similar results in the improvement of structural or functional characteristics such as hypertrophy or strength. However, the different nature of their methods has suggested for years the possibility that different neuromuscular mechanisms could be behind these observed characteristics.

The development of a new technology, such as high-density electromyography (HDEMG), capable of studying new properties previously hidden from assessment methods, such as the speed of nerve impulse propagation or the frequency of motor unit discharge, has allowed a more thorough study of the mechanisms.

This study aims to apply this new study methodology to know what are the mechanisms underlying the changes at the structural and functional level obtained by two different training methods, commonly used, facilitating their understanding, study and subsequent application according to specific needs.

For this reason, the main hypothesis is the generation of different neuromuscular mechanisms and adaptations by executing, for 4 weeks, two different training methodologies, obtaining a dissociation between the results obtained at the structural level (hypertrophy), functional (generation of strength) and HDEMG analysis of the central and peripheral characteristics of the neuromuscular system in each of the programs studied.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18-35 years
  • men

Exclusion criteria

  • physical exercise that involves work of upper limbs during the time of the intervention
  • upper limb injury during the previous 12 months
  • systemic diseases

Treatment and study plan

Speed Loss 20% Strength Training

Other

Strength training based on the control of speed loss in execution.

Reduced Rest Time Strength Training

Other

Strength training based on a protocol that includes reduced rest times between sets.

Primary outcomes

  1. Change from Baseline Mean Discharge Rate of Brachialis Biceps Motor Units at 4 weeks

    Time frame: Baseline and post-intervention (4 weeks after baseline)

    The mean discharge rate of the Brachialis Biceps motor units will be evaluated using a high density electromyography device (HDEMG). For this, the signal produced during isometric contractions at different submaximal force levels (10, 30, 50, and 70%) will be recorded, using an external analog to digital signal converter Sessantaquattro (64-channel EMG amplifier; OT Bioelettronica, Turin, Italy).

Secondary outcomes

  1. Speed of propagation of Brachialis Biceps Motor Units

    Time frame: Baseline and post-intervention (4 weeks after baseline)

    As a measure of evaluation of the peripheral characteristics of the neuromuscular system, the propagation speed of the action potentials produced by an HDEMG device will be evaluated. For this, the signal produced during isometric contractions at different submaximal force levels (10, 30, 50, and 70%) will be recorded, using the external analog to digital signal converter Sessantaquattro

  2. Isometric force of Brachialis Biceps using hand dynamometer

    Time frame: Baseline and post-intervention (4 weeks after baseline)

    The isometric force at 0º, 45º and 90º will be evaluated during a maximum test of 5 seconds using a digital manual dynamometer. The peak force obtained will be obtained.

  3. Isometric force of Brachialis Biceps using s-beam load cell

    Time frame: Baseline and post-intervention (4 weeks after baseline)

    The isometric force at 90º will also be evaluated through an S-type load cell (Biometrics Ltd., Newport, United Kingdom). In addition, the time needed to obtain the peak force achieved will be recorded.

  4. Muscle thickness (thickness) of the brachial biceps using ultrasound

    Time frame: Baseline and post-intervention (4 weeks after baseline)

    Structural changes will be evaluated through an innocuous procedure such as ultrasound. To do this, ultrasound images will be recorded to measure the muscular and adipose thickness of the arm musculature.

  5. Arm circumference

    Time frame: Baseline and post-intervention (4 weeks after baseline)

    A variable related to structural changes such as arm circumference will also be evaluated. For this, the circumference will be recorded through a measuring tape at the average distance between the acromion and the olecranon.

Sponsors and collaborators

Lead sponsor

University of Malaga

Other

Registry information

Official study title

Specific Neurotechnical Strength Training: Randomized Controlled Trial (NeuroTraining)

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Feb 26, 2020
Registry last updated
Dec 7, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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