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OpenTrials
Completed

NCT Number: NCT04623125

Spaced Retrieval as Treatment for Aphasia

Spaced Repetition training has been found to be more effective than massed repetition for individuals with aphasia. This study seeks to examine the relative efficiency of three kinds of spacing for picture-naming training: traditional random presentation, non-adaptive spaced repetition, and adaptive spaced repetition.

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Key information

Conditions

Aphasia, Acquired Anomia Aphasia Aphasia Primary Progressive Brain Diseases Central Nervous System Diseases Communication Disorders Dementia Frontotemporal Dementia Frontotemporal Lobar Degeneration Language Disorders Mental Disorders Nervous System Diseases Neurobehavioral Manifestations Neurocognitive Disorders Neurologic Manifestations Pathological Conditions, Signs and Symptoms Pick Disease of the Brain Signs and Symptoms Speech Disorders

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Baycrest Health Sciences

Toronto, Ontario, M6A 2E1, Canada

About this study

Participants undergo a screening evaluation including the Quick Aphasia Battery (administered via teleconferencing software), and a preliminary picture naming test of approximately 300 pictures, used to select individual items for treatment. Participants then undertake online picture naming training for 30 minutes a day, over two weeks. Pictures are repeated according to three different schedules to be compared: random presentation, non-adaptive spaced repetition, and adaptive spaced repetition. We compare the number of pictures successfully learned and the verbal reaction time for the pictures assigned to the three conditions.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • presence of a post-stroke word finding deficit (i.e. aphasia), or primary progressive aphasia.
  • ability to evaluate the correctness of one's own responses when subsequently provided the with the correct answer

Exclusion criteria

  • diagnosis of a neurological disorder other than post-stroke or primary progressive aphasia
  • inability to evaluate the correctness of ones responses when subsequently provided with the correct answer

Treatment and study plan

Spaced Retrieval Practice

Behavioral

Online picture-naming training with 60 words which the participant experiences word-retrieval difficulties. Cards are shuffled arranged by the computerized training program.

Primary outcomes

  1. Change in Picture Naming performance across conditions

    Time frame: Change from baseline to post-intervention immediately after two weeks of daily sessions, and one month followup.

    Word retention assessed after treatment

Sponsors and collaborators

Lead sponsor

Rotman Research Institute at Baycrest

Other

Collaborators

  • Heart and Stroke Foundation of Canada

Registry information

Official study title

Spaced Retrieval as Treatment for Aphasia: Does Adaptive Spacing Enhance Picture Naming Performance?

Important dates

Study start
2020
Primary completion
2022
Study completion
2022
First posted
Nov 10, 2020
Registry last updated
Mar 29, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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