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NCT Number: NCT01299792

Sonographic Measurement of Bladder Wall Thickness in Patients With Neurogenic Bladder Dysfunction

Video-urodynamic investigations are regarded as the current standard diagnostics for neurogenic bladder dysfunction in patients with spinal cord injury. This examination is exact, but time consuming, costly and associated with the risk of urinary tract infection.

In patients with lower urinary tract symptoms due to benign prostate hyperplasia, sonographic measurement of bladder wall thickness has been demonstrated to be able to replace urodynamic testing for the diagnosis of infravesical obstruction.

Hypothesis: measurement of bladder wall thickness in patients with neurogenic bladder dysfunction due to spinal cord injury is closely related to the known risk factors for upper urinary tract deterioration (bladder compliance, detrusor leak point pressure) in this group of patients and can therefore replace urodynamic examination in selected cases.

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Key information

Conditions

Spinal Cord Injury Central Nervous System Diseases Nervous System Diseases Spinal Cord Diseases Spinal Cord Injuries Trauma, Nervous System Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Swiss paraplecic centre

Nottwil, 6007, Switzerland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • neurogenic bladder dysfunction due to spinal cord injury
  • ability to understand German language
  • willingness and capability to undergo urodynamic testing
  • age > or = 18 years

Exclusion criteria

  • acute urinary infection at the time of examination
  • known bladder tumor or bladder stone
  • age < 18 years
  • not capable to understand aim and purpose of the examination

Treatment and study plan

sonographic measurement of bladder wall thickness

Other

measurement of bladder wall thickness by ultrasound at different filling states of the bladder during urodynamic investigation

Primary outcomes

  1. correlation bladder wall thickness and detrusor compliance

    Time frame: calculated from maximum bladder filling

    measurement of detrusor compliance at maximum bladder volume; measurement of bladder wall thickness at maximum bladder volume

Secondary outcomes

  1. correlation bladder wall thickness and maximum detrusor pressure

    Time frame: measurement at maximum bladder capacity

    correlation between bladder wall thickness and maximum detrusor pressure during the urodynamic storage phase

Sponsors and collaborators

Lead sponsor

Swiss Paraplegic Research, Nottwil

Network

Registry information

Official study title

Sonographic Measurement of Bladder Wall Thickness in Patients With Neurogenic Bladder Dysfunction Due to Spinal Cord Injury

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Feb 18, 2011
Registry last updated
Feb 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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