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OpenTrials
Completed

NCT Number: NCT02380547

Sonographic Evaluation of Diaphragmatic Function in Critical Care Patients With Use of Non Invasive Ventilation

Usefulness of non invasive ventilation in patients extubated after more than 48 hours of invasive ventilation is still in debate except for specific patients (chronic pulmonary disease and chronic heart failure).

Many experimental and clinical studies have shown that diaphragmatic function is depressed by mechanical ventilation in intubated patients.

The investigators will test the hypothesis that non invasive ventilation after extubation may improve diaphragmatic function

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Key information

Conditions

Critical Care Invasive Mechanical Ventilation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Service d'anesthésie- réanimation chirurgicale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient extubated after at least 48 hours of invasive ventilation
  • Requiring non invasive ventilation
  • Consent of patient

Exclusion criteria

  • Diaphragmatic paralysis
  • Neuromuscular disease
  • significant pleural effusion
  • atelectasis requiring bronchoscopy
  • abdominal hypertension

Treatment and study plan

Sonographic diaphragmatic measurements

Other

Other names: Diaphragmatic excursion, Diaphragmatic thickening

Primary outcomes

  1. Diaphragmatic excursion

    Time frame: Before the first NIV session

  2. Diaphragmatic thickening

    Time frame: Before the first NIV session

  3. Diaphragmatic excursion

    Time frame: After the first NIV session

  4. Diaphragmatic thickening

    Time frame: After the first NIV session

  5. Diaphragmatic excursion

    Time frame: After 24 h of NIV use

  6. Diaphragmatic thickening

    Time frame: After 24 h of NIV use

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Acronym: ECHODIA

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Mar 5, 2015
Registry last updated
Mar 22, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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