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NCT Number: NCT06853392

Socket Preservation Using Dentin Graft Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability AUTOGENOUS TOOTH GRAFT WITH COLLAGEN SPONGE ON DENTAL IMPLANT STABILITY

The present study was performed to evaluate socket preservation using collagen sponge with autogenous dentin graft versus collagen sponge with de-mineralised freez-dried bone graft on dental implant stability

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Key information

Conditions

Bone Loss Bone Diseases Bone Diseases, Metabolic Bone Remodeling Disorder Bone Resorption Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases

Age range

25 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 3

Primary location

AL Azhar university for girls

Cairo, Egypt

About this study

in our study we made socket preservation using two different grafts in two groups.

before grafting we took CBCT

we used autogenous dentin graft covered by collagen sponge in one group and demineralized freeze - dried allograft covered with collagen sponge in the other group.

after 6 months we Took another CBCT to assist the dimensional changes and bone density in the alveolar socket after grafting We inserted the implant and during insertion we took a core biopsy with trephine bur with external diameter 3 mm for histological analysis.

After implant insertion we assisted the stability using RFA.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients are free from any systemic diseases.
  • Patients with good oral hygiene.
  • Age range from 25-50 years.
  • Adequate inter arch space .

Exclusion criteria

  • Medications that may affect bone turnover, and bone metabolic diseases.
  • Smoker patients and alcoholics.
  • Patients with parafunctional habits.
  • Patients with active acute infection related to tooth of interest.
  • Patients with a lack of compliance, and serious mental or psychological problems.
  • Pregnant females.

Treatment and study plan

Demineralized freeze dried allograft with collagen sponge

Combination Product

Demineralized freeze dried allograft,filling 2/3 of the socket covered with collagen sponge ,six months, one time

Other names: DFDBA

autogenous dentin graft with collagen sponge

Combination Product

autogenous mineralized dentin graft, filling 2/3 of the socket covered with collagen sponge , six months, one time

Other names: ADG

Primary outcomes

  1. change in radiographic Socket dimensions from base line to 6 months

    Time frame: 6 months following the end of treatment

    CBCT measuring socket dimensions

  2. change in bone density from base line to 6 months

    Time frame: 6 months following the end of treatment

    CBCT measuring bone density within the socket

Secondary outcomes

  1. new bone formation

    Time frame: after six months at the time of implant placement

    Histological analysis for new bone formation by masson trichrome

  2. implant stability

    Time frame: after six months at the time of implant placement

    measuring primary Implant Stability by resonance frequency analysis

Sponsors and collaborators

Lead sponsor

Faculty of Dental Medicine for Girls

Other Gov

Collaborators

  • Beni-Suef University

Registry information

Official study title

Evaluation of Socket Preservation Using Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Mar 3, 2025
Registry last updated
Mar 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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