Saint Joseph University
Beirut, Lebanon
NCT Number: NCT05889377
Post extraction alveolar bone resorption is one of the main challenges that face oral implantologists in their daily surgical practice (1). To palliate to post-extraction resorption, advanced bone grafting and regeneration techniques have been described (2). However, these procedures, although well documented and validated, still have relatively high complication rates and patient morbidity, in addition to the elevated cost and duration of treatment (3). Socket preservation is a very useful technique in order to counter post extraction resorption issues, therefore eliminating the need for future complicated and delicate regeneration procedures (4). Many biomaterials were proposed for socket preservation such as allografts and bovine hydroxyapatite (5). Recently autologous platelet concentrates such as Platelet Rich Fibrin PRF were described as a potential socket filler material (6).
In the proposed protocol, fresh extraction sockets will be either grafted by a bovine bone substitute, a PRF plug or a mixture of both. Sockets will then be clinically and radiographically monitored over time to assess three-dimensional soft and hard tissue stability. Bone quality will be histologically examined at 6 months implant placement. A no graft group will serve as control.
The results of this study may be of major importance since they could give an objective idea of the most efficient socket preservation technique, thus offering simple and secure oral rehabilitation solutions for both patient and practitioner.
Looking for future studies?
Notify Me18 year–62 year
All sexes
Interventional
Not applicable
Beirut, Lebanon
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Socket preservation will be done after tooth extraction. For each group we will use a bone substitute.
Time frame: 4 and 12 months
Comparison of the bone profile change by CBCT dicom files superimposition at different time frame
Time frame: 4 and 12 months
Comparison of the soft tissue profile change by STL files superimposition at different time frame
Saint-Joseph University
Other
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07281053
Ridge Preservation
Sarasota, Florida, United States
View Trial DetailsNCT06896097
Ridge Preservation
Cairo, Cairo Governorate, Egypt
View Trial DetailsNCT03205800
Ridge Preservation
Baltimore, Maryland, United States
View Trial DetailsNCT05437172
Alveolar Bone Loss, Bone Diseases
Cairo, Manial, Egypt
View Trial Details