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Completed

NCT Number: NCT06566417

Social Media as a Risk Tool for HIV Prevention Needs

The impact of effective HIV prevention tools is limited because many people do not know that they are at risk for HIV acquisition, despite the availability of various risk assessment scores and criteria. This proposal aims to use a novel data science approach to assessing HIV prevention needs among 400 young women in Kisumu, Kenya- namely, topic modeling and network analysis of text and/or social media messages (e.g., WhatsApp, Instagram, Twitter). The study will involve in-depth assessment of relevant ethical and logistical factors to ensure appropriate and optimized use of a sentiment analysis tool for implementation in routine clinical care.

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Key information

Conditions

HIV Prevention HIV Preexposure Prophylaxis

Age range

18 year–24 year

Sex eligibility

Female

Study type

Observational

Primary location

KEMRI

Kisumu, Kenya

About this study

In the Social Media as a Risk Tool (SMaaRT) Study, the investigators hypothesize that topic modeling of SMS/social media data combined with network analysis among young women in Kenya will correlate well with existing HIV risk scales and ultimately yield a better understanding of HIV prevention needs. The investigators propose the following aims:

  • Explore ethical factors that may influence analysis of SMS and social media messages. Research assistants will conduct individual qualitative interviews with up to 32 young women (16 who would and 16 who would not provide SMS/social media data, stratified among four clinic sites) and one focus group of five Kenyan bioethicists. Questions will explore ethical concerns from individual and bystander (e.g., contacts involved in SMS/social media) perspectives and differences in ethical issues by type of social media (e.g., conversations vs posts). Follow-up interviews will be conducted with the women who provide SMS and/or social media data (in Aim 2).
  • Conduct topic modeling and network analysis of SMS and social media messages to predict HIV prevention needs among young women in Kenya. Working with four clinical sites in Kisumu, study staff will ask approximately 400 women (ages 18-24) seeking HIV testing, PrEP, and other health services to download six months of SMS/social media messages (e.g., WhatsApp, Instagram, Twitter) as a one-time procedure. For those providing data, research assistants will assess social networks engaged via SMS/social media (e.g., anonymously labeled as peers, sexual partners), administer multiple HIV risk assessments (e.g., VOICE, Wand risk scores), and obtain HIV test results. Data analysts will use automated structural topic modelling to determine "topics" (word clusters) and assess for association with other risk assessments (primary outcome) and HIV test results (exploratory outcome), and will also evaluate the impact of social networks, SMS/social media type, data volume, and language type on outcomes. Data collection and analysis will conform to Aim 1 findings.
  • Assess practical factors that may influence use of a sentiment analysis tool in routine care. In a needs assessment based on Implementation Mapping, research assistants will conduct four focus groups with five staff per clinic and two focus groups with five young women each to explore staffing best suited to implement a sentiment analysis tool and how it could be best integrated into routine care. The investigators will also assess available resources to determine optimal efficiency in developing a preliminary implementation strategy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Identifying as a young woman (age 18-24 years)
  • Attending clinic for any health services, including PrEP and HIV testing
  • Smart phone ownership
  • Ability to understand Kiswahili, DhoLuo, and/or English
  • Use of SMS, WhatsApp, and/or other types of social media

Exclusion criteria

  • Inability to provide informed consent (e.g., intoxication, developmental delay)

Treatment and study plan

Primary outcomes

  1. Association of artificial intelligence measure datasets with the VOICE risk score

    Time frame: 6 months

    Analysts will examine 6 months of SMS/social media message content from each of the 400 study participants using three computational linguistic methods: 1) sentiment, valence, and arousal analysis; 2) topic modeling; 3) simple textual counts. Analysts will also perform network analysis with up to 20 contacts from each participant to understand how often and with which parties the participant communicates most frequently. These networks will be examined temporally to see if any of the connections have grown or weakened over time.

    From these analyses, the investigators will generate multiple measure datasets to compare with the VOICE risk score (i.e., a combined assessment of HIV risk based on age, marital status, sexual partner support, sexual partner sexual behavior, and alcohol use), as assessed in the study participants at the time of SMS/social media data collection.

  2. Association of artificial intelligence measure datasets with the Wand risk score

    Time frame: One day

    The investigators will compare the above-noted measure datasets with the Wand risk score (i.e., a combined assessment of HIV risk based on age, marital status, age at sexual debut, number of sexual partners, use of injectable contraception, and history of sexually transmitted infections), as assessed in the study participants at the time of SMS/social media data collection.

Secondary outcomes

  1. Association of artificial intelligence measure datasets with HIV test results

    Time frame: One day

    The investigators will compare the above-noted measure datasets with the HIV test results obtained from the study participants at the time of data collection.

Sponsors and collaborators

Lead sponsor

Massachusetts General Hospital

Other

Collaborators

  • KEMRI-Wellcome Trust Collaborative Research Program
  • Kenya Medical Research Institute
  • National Institute of Mental Health (NIMH)
  • North Carolina State University

Registry information

Official study title

Use of Sentiment Analysis and Social Media to Understand HIV Prevention Needs Among Young Women in Kenya

Acronym: SMaaRT

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 22, 2024
Registry last updated
Nov 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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