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Completed

NCT Number: NCT03918902

Snuff Use, Smoking, Periodontitis and Mortality: 30-year Cohort Study From Sweden

Smoking and dual using associated with poor periodontal health.

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Key information

Conditions

Tobacco Use Behavior Mouth Diseases Periodontal Diseases Periodontitis Stomatognathic Diseases

Age range

31 year–40 year

Sex eligibility

All sexes

Study type

Observational

About this study

Aim: To investigate how snuff use, smoking and risk behaviour affect periodontal health and mortality in a Swedish cohort, hypothesizing that they indeed have a poor impact and increase the risk of death.

Material and methods: Study cohort of 1080 subjects aged 31 to 40 years (528 men and 552 women) from Stockholm area was clinically examined in 1985 and followed for mortality until 2015. Associations between periodontal health parameters, snuff use, smoking and age of death were analysed by classifying all subjects into four groups: "dual-users" (current snuffers and current smokers); "pure snuffers" (current non-smoking snuffers); "pure smokers" (current non-snuffing smokers) and "non-users" (non-snuffers, non-smokers). SPSS was used for analyses.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • In 1985-1986 a sample was selected from the registry file of all inhabitants of the Stockholm area, of people born on the 20th of any month from 1945 to 1954.The sample comprised 3200 people. They were informed about the purpose of the study and called for clinical investigation. 1681 (52.5%) individuals, 840 men and 841 women, participated in the study. Subjects had different socio-economic and health backgrounds.

Exclusion criteria

  • Other people. Any disease was not an exclusion criteria.

Treatment and study plan

Qestinnaires

Behavioral

Questionnaires

Primary outcomes

  1. Deep periodontal pockets (5mm or over)

    Time frame: 1985

    Periodontal pockets were measured from all teeth and from six surfaces with a Hu-Friedy (PCPUNC 15) periodontal probe (Hu-friedy, Chicago, Ill., USA).

  2. Calculus index

    Time frame: 1985

    Calculus index was scored from 0 (no calculus) to 3 (abundant calculus) according to Greene & Vermillion.

  3. Missing teeth

    Time frame: 1985

    Missing teeth were calculated my dentist in clinical examination.

  4. Premature death

    Time frame: From year 1985 to year 2015

    The Swedish National Death Register listing the cumulated causes of all deaths was used in the analyses.

  5. Plaque index

    Time frame: 1985

    Plaque index was scored from 0 (no plaque) to 3 (abundant plaque).

  6. Gingival index

    Time frame: 1985

    Gingival index was scored from 0 (no gum bleeding) to 3 (abundant gum bleeding).

Sponsors and collaborators

Lead sponsor

University of Helsinki

Other

Collaborators

  • Karolinska Institutet

Registry information

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Apr 18, 2019
Registry last updated
Apr 18, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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