Smoking Cessation in Alcoholism Treatment

This study is designed to increase understanding of the processes that affect the treatment outcome of individuals with both alcohol and nicotine dependence. Treatment outcome methodology will be combined with a computerized self-monitoring methodology to examine the extent to which smoking serves as a cue for alcohol craving and/or as a response to alcohol craving in treated alcoholics. Subjects will be veterans participating in the Substance Abuse Day Programs at the Newington and West Haven campuses of the VA Connecticut Healthcare System. Nonveteran women will be recruited from the community and enrolled in the day program. Subjects will be randomly assigned to one of the following two conditions: (1) intensive smoking cessation therapy (counseling plus nicotine replacement using nicotine patches) concurrent with alcohol treatment, or (2) brief smoking cessation advice concurrent with alcohol treatment.

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Key information

Conditions

Alcoholism Alcohol-Related Disorders Behavior Chemically-Induced Disorders Mental Disorders Smoking Substance-Related Disorders

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Substance Abuse Treatment Center, VA Medical Center

West Haven, Connecticut, 06516, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Meets criteria for alcohol dependence within the past three months, and criteria for nicotine dependence.
Smoking at least 10 or more cigarettes per day for the past year.
Seeking treatment for both alcohol and nicotine dependence.
Minimum 1 week of alcohol abstinence and substance abuse day treatment attendance.
Willing to provide names of two individuals who can help locate the subject at follow-up.
Willing to provide name of one individual who can provide collateral information about alcohol and tobacco use.

Exclusion criteria

Other substance use disorder meeting criteria for dependence.
Acute medical or psychiatric disorder requiring inpatient treatment.
Taking medications known to influence alcohol urges (naltrexone, disulfiram).
Medical problems that would contraindicate nicotine patch use.
Allergy or hypersensitivity to nicotine or to adhesives used in transdermal delivery systems.
Use of other nicotine products such as cigars, pipes, or smokeless tobacco.
Severe generalized skin disorder.
Myocardial infarction within 3 months prior to study entry.
Unstable angina.
Pregnant or lactating females, or females who are not practicing a medically accepted form of contraception.
Impaired vision or hearing which would interfere with using a hand-held computer.
Reading ability below fifth grade level.
Lack of reliable transportation to the treatment site, or living more than 1 hour from treatment site.
Homeless or unstable residence.
Plan for future admission to residential treatment.

Treatment and study plan

nicotine replacement patch

Drug

Sponsors and collaborators

Lead sponsor

Yale University

Other

Collaborators

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Registry information

Official study title

Field Study of Smoking Cessation in Alcoholism Treatment

Important dates

Study completion: 2002
First posted: Nov 3, 1999
Registry last updated: May 19, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed