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Completed

NCT Number: NCT05016856

Smart Reminders to Promote Home-based Cognitive Training

This study will examine whether among older adults an adaptive and personalized reminder system can better support adherence to home-based cognitive training over typical reminder systems.

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Key information

Age range

65 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Psychology, Florida State University

Tallahassee, Florida, 32306-4301, United States

About this study

Many cognitive training interventions are associated with poor adherence, and poor adherence is associated with fewer benefits. Further, poor adherence in cognitive intervention studies can interfere with answering fundamental questions regarding intervention efficacy. This study will compare the effects of non-adaptive and smart adherence support systems. Participants will be asked to engage in frequent home-based cognitive training on a computer tablet. In the smart adherence support condition, participants will receive adaptive and tailored reminders based on dynamic algorithms that deploy reminders in a way that considers participant preferences, days and times of previous successful engagement, the success of previous reminder attempts, and answers to brief questions contained within reminder prompts. Parameter weights for these variables will be adjusted dynamically over a 6-month assessment period to ensure that reminders are deployed when they are most likely to be acted upon. This study will investigate adherence to training sessions, multiple times each week for 6 months, representing a large challenge to adherence. Participants will be randomly assigned to one condition or another, and adherence at home will be monitored. This will be an Individually Randomized Group-Treatment Trial (IRGT).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 65 years of age or older
  • normal or corrected to normal visual acuity
  • must pass a dementia screening

Exclusion criteria

  • Parkinson's, Alzheimer's disease, or any other neurodegenerative disease
  • terminal illness
  • blindness or deafness
  • severe motor impairment
  • not living in the Tallahassee area for the entire 6 month study period
  • unable to read at or above 6th grade level

Treatment and study plan

Adherence Promotion With Person-centered Technology (APPT) System

Behavioral

A personalized and adaptive text message reminder system.

Standard Reminder System (Active Control)

Behavioral

A typical text message reminder system.

Primary outcomes

  1. Adherence (session number)

    Time frame: 6 months

    Number of sessions over 6 months

  2. Adherence (session length)

    Time frame: 6 months

    Number of sessions reaching at least 80% of the assigned session duration over 6 months

  3. Adherence (holidays)

    Time frame: 6 months

    Number of extended gaps in between sessions over 6 months

Secondary outcomes

  1. Objective Cognition (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    A composite measure of objective cognitive ability

  2. Subjective Cognition (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    A composite measure of subjective cognitive deficit

  3. Self-Efficacy (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    A composite measure of self-efficacy (beliefs held about ability to complete tasks)

  4. Technology Proficiency (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    A composite measure of proficiency with technology

  5. Perceived Training Efficacy (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    A composite measure of belief in the the efficacy of cognitive training

  6. Personality (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    Measure of stable traits

  7. Dementia Worry (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    A composite measure of anxiety over cognitive decline

  8. Busyness Scale (predictor of adherence)

    Time frame: Assessed at baseline, predicting adherence variables over 6 months

    Self-reported environmental demands of day-to-day life

Other outcomes

  1. Interview

    Time frame: 6 months

    Interview assessing experience in study

Sponsors and collaborators

Lead sponsor

Florida State University

Other

Registry information

Official study title

Adherence Promotion with Person-centered Technology (APPT): Promoting Adherence to Cognitive Intervention

Important dates

Study start
2022
Primary completion
2024
Study completion
2025
First posted
Aug 23, 2021
Registry last updated
Feb 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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