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Completed

NCT Number: NCT05349357

Slider Versus Tensioner Neural Mobilization in Diabetic Peripheral Neuropathy

Neurodynamics, i.e., the mobilization of the peripheral nervous system, is a physical approach to the treatment of pain; the method relies on influencing pain physiology via mechanical treatment of neural tissues and the non-neural structures surrounding the nervous system. Neural mobilization (NM) is used to treat various disorders of the nervous system concerning the length and mobility of peripheral nerves, as the nerve mobilizing refers to techniques that help to reestablish motion between a nerve and its surrounding soft tissues, thus to treat the nerves that have become entangled within the soft tissue, as it leads to tension release on a nerve by stretching and pulling one end of the nerve during keeping the other end in a relaxed state.

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Key information

Conditions

Diabetic Peripheral Neuropathic Pain

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

DHQ Hospital

Mianwali, Punjab Province, Pakistan

About this study

The neurodynamic technique both sliders and tensioners results in changes of the mechanical or physiological function of nerve tissues along with the interface; restoring pressure gradients, relieving hypoxia and pain resulting in reducing associated symptoms.

Through clinical reasoning the nervous system seems to be the logical place for treatment and explanations and previous descriptions of this method have clarified the overall impact on quality of life in diabetic peripheral neuropathy but it doesn't discuss which technique of neural mobilization is more effective and its effects on diabetic peripheral neuropathic population. Within this reasoning it is important to determine which neurodynamic technique is more effective in improving quality of life and reduce pain in patients with diabetic peripheral neuropathy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patient having≥12score on Self report Leads Assessment of Neuropathic Symptoms and Sign
  • Patients with lower limb pain ≥4 to ≤7 on NPRS

Exclusion criteria

  • Diabetic foot ulcer
  • Complex regional pain syndrome
  • Infection in lower limb
  • Lower extremity amputation
  • Discogenic pain
  • Restricted joint deformity
  • Dependency on chemical or drugs
  • Pregnancy

Treatment and study plan

Sliding Neural mobilization

Other

Sliding neural mobilization to femoral, sciatic and tibial nerve

Tensioner Neural mobilization

Other

Tensioner neural mobilization to femoral, sciatic and tibial nerve

Stretching exercises

Other

Stretching exercises

TENS

Device

TENS

Primary outcomes

  1. Michigan neuropathy screening instrument

    Time frame: 3 weeks

    For screening the neuropathy; The MNSI questionnaire is self-administered. Responses are added to obtain a total score. 'Yes' responses to questions 1-3, 5-6, 8-9, 11-12, 14-15 are each counted as one point. 'No' responses to questions 7 and 13 each count as one point. Question 4 was considered to be a measure of impaired circulation and question 10 a measure of general asthenia and were not included in the published scoring algorithm. A score of ≥ 7 was considered abnormal. All 15 questions were included in the new scoring algorithms.

  2. Numerical Pain Rating Scale

    Time frame: 3 weeks

    Quantify the pain ranging from 0 to 10 in which zero means no pain and 10 severe pain

Secondary outcomes

  1. Quality of Life SF-36

    Time frame: 3 weeks

    to assess the quality of life, SF-36 ; Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower the score the more disability. The higher the score the less disability i.e., a score of zero is equivalent to maximum disability and a score of 100 is equivalent to no disability.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Compare the Effects of Sliding With Tensioner Technique of Neural Mobilization in Diabetic Peripheral Neuropathy Patients

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Apr 27, 2022
Registry last updated
Mar 9, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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