Skin Sympathetic Nerve Activity and Sympathetic Tone

There are many sympathetic hyperactivity diseases in the investigators' clinical practice. However, the conventional method to measure the sympathetic nerve activity had many limitations such as clinical application, data interpretation and even therapeutic manipulation. Therefore the investigators would like to develop a non-invasive method to record the sympathetic nerve activity in the investigators' study that can help gathering the sympathetic nerve activity easily in the investigators' daily clinical situation. By the determination of sympathetic nerve activity status, the health caregiver can understand the disease more.

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Key information

Conditions

Nerve; Disorder, Sympathetic Healthy

Age range

20 year–85 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Sympathetic hyperactivity diseases included: hypertension, heart failure atherosclerotic diseases, arrhythmias, cardiomyopathy, pulmonary hypertension, chronic obstructive pulmonary disease, sleep apnea, pulmonary embolism, hepatitis, liver cirrhosis, hepatopulmonary syndrome, hepatorenal syndrome, renal failure, nephritis, irritable bowel syndrome.
Healthy Volunteers

Exclusion criteria

Pregnant

Treatment and study plan

Primary outcomes

Skin Sympathetic Nerve Activity

Time frame: 12 hours

The Sympathetic Nerve Activity Recording from the skin of the subjects in the day time.

Secondary outcomes

ventricular arrhythmia

Time frame: 24 to 72 hours

The electrocardiogram recording from the telemetry.
Mortality

Time frame: 1 to 12 months

The mortality will be accessed by the chart review and telephone access
Morbidity

Time frame: 1 to 12 months

The morbidity will be accessed by the chart review and telephone access

Sponsors and collaborators

Lead sponsor

Kaohsiung Medical University Chung-Ho Memorial Hospital

Other

Registry information

Official study title

Using Skin Sympathetic Nerve Activity to Estimate Sympathetic Tone in Human

Important dates

Study start: 2016
Primary completion: 2026
Study completion: 2026
First posted: Aug 9, 2017
Registry last updated: Oct 4, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed