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Completed

NCT Number: NCT06589284

Skin Glue Versus Suture for Securing Radial Arterial Lines

Prior investigators have evaluated the use of 2-octyl cyanoacrylate (glue) as a method to secure a variety of venous catheters including central/peripheral lines. There is a paucity of research evaluating the use of glue for arterial catheters. The investigators conducted a pilot study to test the null hypothesis that there would be no difference in failure rates between radial arterial lines (r-a-line) secured with glue vs. suture.

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Key information

Conditions

Arterial Catheters Catheter Related Complication

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHRISTUS Spohn Hospital Corpus Christi - Shoreline

Corpus Christi, Texas, 78404, United States

About this study

This was a prospective, randomized, controlled, trial for which the investigators enrolled a convenience sample of consenting, non-pregnant, adult patients who received an r-a-line in the ICU or ED at a community-based, teaching hospital. After randomization, lines were secured with either silk 0-0 suture or 2-octyl cyanoacrylate and, then, covered by chlorhexidine gluconate dressing. Patients were followed for duration of line placement and for the occurrence of premature line failure. Categorical data were analyzed by chi-square; continuous data by t-tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be at least 18 years of age
  • Require invasive blood pressure monitoring via radial arterial catheter

Exclusion criteria

  • Under 18 years of age
  • Pregnant

Treatment and study plan

Silk 0-0 suture covered by chlorhexidine gluconate dressing

Procedure

The specific intervention will be securing radial arterial catheters with either skin adhesive or suture material. Both are largely accepted to be standard of care but to date there is a paucity of literature directly comparing the two for radial arterial lines. During the intervention the placement of radial arterial catheters will be done via standard sterile procedure and using seldinger technique which involves using a guidewire to slide the arterial catheter into the radial artery. After the catheter is placed, it will be secure with either straight suture with a cutting needle or via skin adhesive. Following securement, the area will be cleaned and a Tegaderm dressing with biopatch will be placed over the catheter. Data will be collected immediately after the procedure including length of procedure and complications as well as via chart review to determine the length of time the catheter was in place and evidence of premature failure.

2-octyl cyanoacrylate covered by chlorhexidine gluconate dressing

Procedure

The specific intervention will be securing radial arterial catheters with either skin adhesive or suture material. Both are largely accepted to be standard of care but to date there is a paucity of literature directly comparing the two for radial arterial lines. During the intervention the placement of radial arterial catheters will be done via standard sterile procedure and using seldinger technique which involves using a guidewire to slide the arterial catheter into the radial artery. After the catheter is placed, it will be secure with either straight suture with a cutting needle or via skin adhesive. Following securement, the area will be cleaned and a Tegaderm dressing with biopatch will be placed over the catheter. Data will be collected immediately after the procedure including length of procedure and complications as well as via chart review to determine the length of time the catheter was in place and evidence of premature failure.

Primary outcomes

  1. Length of time which the catheter remained in place

    Time frame: 12 months

    Primary outcomes measured were length of time of which the catheter remained in place and causes of premature failure, if it occurred.

  2. Cause of premature failure (if occurred)

    Time frame: 12 months

    Primary outcomes measured were length of time of which the catheter remained in place and causes of premature failure, if it occurred.

Secondary outcomes

  1. Evaluation of patient demographics for line failure

    Time frame: 12 months

    Secondary outcomes included an evaluation of patient and line placement demographics for line failure between both suture and skin glue groups.

  2. Evaluation of line placement for line failure

    Time frame: 12 months

    Secondary outcomes included an evaluation of patient and line placement demographics for line failure between both suture and skin glue groups.

Sponsors and collaborators

Lead sponsor

CHRISTUS Health

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 19, 2024
Registry last updated
Sep 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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